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In Vivo Imaging Instruments

Whether you’re trying to understand biology pathways, monitor disease progression, or evaluate drug candidates earlier in drug development, our wide portfolio of preclinical imaging systems are designed to meet your research needs.

Offering high-throughput capability and sensitivities to image down to a single cell our IVIS® technology continues to pave the way in small animal optical imaging.

The Quantum GX3 can be used for a diverse array of research applications such as lung and cardiac imaging made possible through fast image-based gating techniques, in vivo and ex vivo bone imaging, and other soft tissue applications.

In addition to optical and microCT modalities, we also offer the world’s first ultrasound system that combines automated, hand-free technology with high-throughput capability - the innovative Vega® preclinical ultrasound system that delivers 2D and 3D images in just a few minutes.

For research use only. Not for use in diagnostic procedures.

With over 20 years experience in preclinical in vivo imaging, our industry leading IVIS optical imaging systems are the most published platform for bioluminescence and fluorescence imaging with over 20,000 peer-reviewed publications.

Our Quantum GX3 standalone microCT system features a highly sensitive, high resolution flat panel detector enabling fast scanning with high image signal-to-noise and low radiation exposure for repeated CT scans used in longitudinal imaging studies.

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Vega® preclinical ultrasound
  • Hands-free, automated transducer positioning and movement
  • High speed, high-throughput performance with 3 mice scanning in just a few minutes
  • Hands-free, automated transducer positioning and movement
  • High speed, high-throughput performance with 3 mice scanning in just a few minutes
  • 3D Widefield acquisitions enabling whole subject imaging
  • Standard B-mode and M-mode capability
  • Shear Wave Elastography (SWE) mode for quantifying and evaluation tissue stiffness
  • Acoustic angiography mode for visualizing microvasculature
  • Fits on the benchtop
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IVIS® Lumina S5 & X5
  • High-sensitivity 2D optical imaging (bioluminescence and fluorescence)
  • High-throughput format with a 20 x 20 FOV sufficient for imaging 5 mice simultaneously
  • High-sensitivity 2D optical imaging (bioluminescence and fluorescence)
  • High-throughput format with a 20 x 20 FOV sufficient for imaging 5 mice simultaneously
  • High resolution, low dose X-ray with optical overlay (IVIS Lumina X5 only)
  • Compact design that fits on your benchtop
  • Unique animal handling accessories and software tools to streamline throughput
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IVIS® Lumina III series
  • 2D optical imaging (bioluminescence and fluorescence)
  • Low-dose X-ray with optical overlay (IVIS Lumina XRMS only)
  • 2D optical imaging (bioluminescence and fluorescence)
  • Low-dose X-ray with optical overlay (IVIS Lumina XRMS only)
  • Images up to 3 mice simultaneously
  • Compact design that fits on your benchtop
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IVIS® Spectrum and IVIS Spectrum 2 series
  • High sensitivity 2D and 3D bioluminescence & fluorescence imaging
  • High throughput simultaneous imaging of up to 10 mice
  • High sensitivity 2D and 3D bioluminescence & fluorescence imaging
  • High throughput simultaneous imaging of up to 10 mice
  • Fast data acquisition for rapid visualization of images in real-time
  • Two powerful modes of fluorescence excitation— epi-fluorescence and trans-illumination
  • Proprietary spectral unmixing algorithms for autofluorescence removal and multiplex imaging
  • Easy, one-click co-registration with the Quantum GX3 microCT system
  • Broadly adopted, easy to use, and intuitive, Living Image® visualization and analysis software
  • Integrated low-dose, ultra-fast microCT (IVIS SpectrumCT 2 only)
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Quantum GX3 microCT imaging system
  • Superior spatial resolution of 5 microns
  • Wide FOV range from 8 mm to 86 mm
  • Superior spatial resolution of 5 microns
  • Wide FOV range from 8 mm to 86 mm
  • Improved image-based respiratory gating
  • Proprietary active ring reduction
  • Continuous and step scanning modes
  • Seamless co-registration with the IVIS 3D optical imaging system
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Literature - Publication Review
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency
AAV Surfactant protein SP-B adeno-associated virus IVIS
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Case Study
A novel non-Invasive in vivo tool for the assessment of NASH
NASH NAFLD Non-alcoholic fatty liver disease. liver disease metabolic disease liver fibrosis liver steatosis cirrhosis
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Brochure
A whole new perspective on ultrasound imaging
Vega sonovol ultrasound preclinical ultrasound shear wave elastography elastography acoustic angiography B-mode M-mode brightness mode motion mode 3D ultrasound 4D ultrasound liver stiffness sonoEQ
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Technical Note
Adaptive Fluorescence Background Subtraction for IVIS systems
Adpative Fluorescence Background subtraction IVIS IVIS Imaging Technical Notes IVIS tech notes.
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Technical Note
APP_Protocol_MMPSense 750 FAST
MMP Matrix metallo protease matrix-metallo protease matrix metalo matrix metalo protease
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Literature - Publication Review
Applications of In Vivo bioluminescence imaging for SARS-CoV-2
SARS-CoV-2 SARS COVID in vivo imaging bioluminescent imaging
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Case Study
Assessment of MYC-driven progression of small cell lung cancer
lung cancer small cell lung cancer microCT quantum GEMM in vivo imaging
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Technical Note
AutoExposure
autoexposure IVIS imaging living image
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Case Study
Automated ultrasound for non-invasive in vivo evaluation of liver disease progression in mice
liver disease NASH NAFLD steatosis liver fibrosis Vega
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Literature - Publication Review
Bacteria Eat Nanoprobes for Aggregation-enhanced Imaging and Therapy
infectious diseases nanoprobes IVIS
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Flyer
Best practices for designing an effective in vivo fluorescence imaging study
IVISense fluorescent probes fluroescent dyes fluorescent labels probe guide probe selector oncology probes oncology research tumor burden tumor metastasis cell death angiogensis
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Whitepaper
Bioluminescence Resonance Energy Transfer (BRET) to monitor protein-protein interactions
BRET bioluminescence resonance energy transfer PPI PPIs protein-protein interactions non-invasive in vivo imaging optical imaging
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Literature - Publication Review
Biopolymers Codelivering Engineered T Cells and STING Agonists can Eliminate Heterogenous Tumors
immuno oncology immune onclology immuno-oncology STING CAR T CAR-T CAR T cells adoptive cell therapy solid tumors engineered T cells T cells
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Literature - Publication Review
Clinically translatable cytokine delivery platform for eradication of intraperitoneal tumors
Cytokines IL-2 interleukin-2 proinflammatory cytokines cytokine delivery IVIS optical imaging IVISbrite D-luciferin
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Application Note
Comparison of vascular fluorescent imaging agents in oncology and inflammation research
IVISense IVISense Edema IVISense Vascular vascular probe vascular imaging AngioSense Superance fluorescent probes fluorescence imaging
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Flyer
Complete Virology Solutions Infographic
Virology Solutions Detection Neuralization Testing Infectious Disease
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Literature - Publication Review
Evaluating a novel nanoparticle platform for controlled liraglutide release in a Type II diabetes mouse model
Diabetes type II diabetes metabolic metabolic disease Lira Liraglutide in vivo imaging optical imaging IVIS
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Application Note
Imaging gastric emptying with IVISense™ Gastrointestinal 750 fluorescent probe
IVISense Gastointestinal GastroSense gastric emptying gastric motility fluroescence imaging
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Application Note
Imaging Hepatocellular Liver Injury using NIR-labeled Annexin V
liver toxicity drug induced liver toxicity DILI annexin IVISense Annexin APAP acetaminophen toxicity
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Application Note
Imaging oncolytic virus infection in cancer cells
virus viruses oncolytic cancer cancer cells oncolytic virus Sindbis pseudovirus bioluminescence imaging optical imaging IVIS
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Literature - Publication Review
Impairment of a Distinct Cancer-Associated Fibroblast Population Limits Tumor Growth & Metastasis
IVIS optical imaging Celigo cytometry Operetta high-content screening HCS fibroblasts cancer activated fibroblasts
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Literature - Publication Review
Improving engineered T cell efficacy for treating solid tumors through epigenetic modulation
T-cells epigenetics engineered t-cells t-cell cytotoxicity Opera Phenix IVIS epigenetic modulation G9a/GLP inhibition G9a/GLP
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Literature - Publication Review
In vivo imaging of influenza virus infection in immunized mice
influenza virus viral research in vivo imaging virus research vaccinations vaccines
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eBook
In vivo imaging solutions
in vivo imaging solutions eBook pre-clinical imaging solution provider eBook for in vivo imaging solutions preclinical in vivo Imaging optical imaging microCT ultrasound imaging instruments in vivo imaging solutions preclinical imaging pre-clinical imaging imaging reagents imaging probes IVIS IVISbrite IVISense VesselVue quantum vega
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eBook
In vivo imaging solutions
in vivo imaging solutions eBook pre-clinical imaging solution provider eBook for in vivo imaging solutions preclinical in vivo Imaging microCT Vega
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