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IVIS SpectrumCT 2 In Vivo Imaging System
This product replaces the IVIS® SpectrumCT system (part number 128201).
For ultimate ease and flexibility, the IVIS SpectrumCT 2 in vivo optical imaging system integrates 2D & 3D bioluminescence and fluorescence imaging with low-dose CT combining both molecular functional and anatomical in vivo imaging into single system.
For research use only. Not for use in diagnostic procedures.
Product information
Overview
The IVIS SpectrumCT 2 in vivo optical imaging system is an integrated platform that combines the full suite of IVIS optical features including; spectral unmixing and 2D and 3D quantitative bioluminescence & fluorescence imaging, with fast, low dose microCT imaging.
Similar to the IVIS Spectrum 2 (part number CLS158736) optical imaging system, the IVIS SpectrumCT 2 incorporates a CCD camera with eXcelon® coating that enables detection of more signal at higher efficiency across a broader spectrum of wavelengths.
The simple user interface along with advanced visualization and analysis tools are driven by our market leading, easy to use Living Image® software. The IVIS SpectrumCT 2 enables longitudinal workflows to characterize disease progression and therapeutic effect throughout the complete experimental time frame with both quantitative CT and optical reconstructions. Fast imaging and the ability to image multiple animals offers the throughput required to scan large cohorts of animals quickly and draw sound conclusions from your experimental data.
Additional product information
Features and benefits
High sensitivity
Exclusivity to patented CCD camera with eXcelon coating for high sensitivity imaging
Combined modalities
Integrating optical imaging with microCT for simultaneous functional and anatomical studies in a single system
High throughput
Standard 5 mice configuration or up to 10 mice capacity using optional manifold
Rapid imaging
Fast data acquisition allows quick visualization of images in real-time
Trans-illumination
Imaging below the specimen for sensitive detection and quantification of deep fluorescent sources
Epi-illumination
Imaging above the specimen ideal for high throughput workflow
Spectral unmixing
Remove autofluorescence & easily identify, separate, and quantify multiplexed fluorescent signals
Analysis software
Broadly adopted, easy to use, and intuitive, Living Image visualization and analysis software
High-performance CCD camera
The camera and coating facilitate detection of more signal at higher efficiency across a broader spectrum of wavelengths throughout the visible and NIR spectrum - giving you:
- Improved signal-to-noise ratio for both bioluminescent and fluorescent signals
- Increased bandwidth to encompass a wider range of NIR fluorescent probes
Camera highlights
- Patented eXcelon® coating
- Back-illuminated, thermoelectrically cooled (-90°C) CCD
- High quantum efficiency (peak >95%)
- 2048 x 2048 imaging pixels with 13.5 micron pixel size
- Low read noise
Fast, low-dose microCT
Automated optical and high-performance, low-dose microCT integration enabled through:
- Constant horizontal gantry motion and the flat panel detector
- Stable revolving animal platform table that rotates 360° to acquire full 3D data
- Maintaining an average dose per scan at 13mGy, ideal for longitudinal studies
- Simultaneous scanning of up to 2 mice
- Fast scanning and reconstruction times of less than a minute
Bring your in vivo images to life with Living Image software
Broadly adopted imaging software that sets the industry standard for ease of use and flexibility
- Comprehensive set of tools for 2D and 3D data analysis
- One click 3D reconstructions
- Spectral unmixing algorithms to easily obtain and separate simultaneous fluorescent readouts or remove unwanted autofluorescence
- Co-register optical imaging with other modalities (e.g., CT, MRI, SPECT, PET)
- Auto settings for easy image acquisition
- Batch processing analysis tools
- Generation of animated movies and publication ready figures
- Flexible remote review for convenient offline analysis of data sets
- Included in IVIS purchase
Which IVIS system is best for your research?
| IVIS spectrum 2 | IVIS spectrumCT 2 | IVIS lumina S5 | IVIS lumina X5 | IVIS lumina III | IVIS lumina LT | IVIS lumina XRMS | |
|---|---|---|---|---|---|---|---|
| Capacity | Up to 10 mice* | Up to 10 mice* | Up to 10 mice* | Up to 10 mice* | Up to 5 mice** | Up to 5 mice** | Up to mice |
| Benchtop format | ✔ | ✔ | ✔ | ✔ | ✔ | ||
| 2D Bioluminescence / Fluorescence | ✔/✔ | ✔/✔ | ✔/✔ | ✔/✔ | ✔/✔ | ✔/✔ | ✔/✔ |
| 3D Bioluminescence / Fluorescence | ✔/✔ | ✔/✔ | |||||
| Enhanced Fluorescence capabilities | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | |
| Integrated standard x-ray | ✔ | ||||||
| Integrated high resolution x-ray | ✔ | ||||||
| Integrated CT | ✔ | ||||||
| Optical FOV (cm) (Nominal) | 4-22.5 | 4-22.5 | 10-22.5 | 10-22.5 | 5-12(2.6**) | 5-12(2.6**) | 5-12 |
| Wavelength range (nm) | 415-850 | 415-850 | 410-865 | 410-865 | 410-865 | 415-875 | 410-865 |
| For additional comparison information please refer to the IVIS Comparison flyer under the ‘Resources’ tab *Using optional manifold kit **Using expansion lens |
|||||||
Specifications
| Height |
206.0 cm
|
|---|---|
| Portable |
No
|
| Width |
65.0 cm
|
| Brand |
IVIS
|
|---|---|
| Imaging Modality |
microCT Imaging
Optical Imaging
|
| Optical Imaging Classification |
Bioluminescence Imaging
Fluorescence Imaging
|
Video gallery
Resources
Literature - Publication Review
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency
Surfactant Protein B (SP-B) deficiency is an uncommon, autosomal recessive lung disorder in term infants. This inability to...
Brochure
Biologics workflow solutions
Precision biologics are playing an increasingly powerful role as part of therapeutic strategies such as monoclonal antibodies...
Literature - Publication Review
Evaluating a novel nanoparticle platform for controlled liraglutide release in a Type II diabetes mouse model
A large percentage of Type 2 diabetes mortality is related to cardiovascular complications. Consequently, there is a critical need...
Application Note
Imaging oncolytic virus infection in cancer cells
Aside from the traditional small-molecule chemotherapeutics or targeted therapy agents that have been widely used in the clinic...
Literature - Publication Review
Improving engineered T cell efficacy for treating solid tumors through epigenetic modulation
The high heterogeneity, lack of tumor-specific targets, and immunosuppressive tumor microenvironment of solid tumors are all...
Literature - Publication Review
In vivo imaging of influenza virus infection in immunized mice
Annual epidemics of influenza have occurred throughout history causing tens of millions of deaths. Even a run-of-the-mill...
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