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IVIS Lumina LT In Vivo Imaging System

The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.

For research use only. Not for use in diagnostic procedures.

Need D-Luciferin substrate in powder or ready-to-use injectable format?

Overview

The standard instrument is equipped with full bioluminscence, radioisoptic (Cerenkov) imaging capabilities for 2D imaging and standard fluorescence. For more sophisticated fluorescent models, the Lumina LT can be upgraded to a full Lumina Series III.

Features/Benefits:

  • Bioluminescence
  • Fluorescence
  • Radioisotopic Cerenkov Imaging
  • Compute Pure Spectrum Spectral Unmixing
  • DyCE Imaging (Optional Upgrade)
  • Extended NIR Range 150W Tungsten EKE
  • Absolute Calibration to NIST® Standards

Specifications

Height
104.0 cm
Width
48.0 cm
Brand
IVIS
Imaging Modality
Optical Imaging

References

  • Wang et al (2021). LncRNA SPOCD1-AS from ovarian cancer extracellular vesicles remodels mesothelial cells to promote peritoneal metastasis via interacting with G3BP1. J Exp & Clin Res. 40(101). https://doi.org/10.1186/s13046-021-01899-6
  • Zhong et al (2021). Calcium phosphate engineered photosynthetic microalgae to combat hypoxic-tumor by in-situ modulating hypoxia and cascade radio-phototherapy. Thernostics. 11(8): 3580–3594. https://dx.doi.org/10.7150%2Fthno.55441
  • Li et al (2020). High selective distinguishable detection GSH and H2S based on steric configuration of molecular in Vivo. Dyes & Pigments. 172;107826. https://doi.org/10.1016/j.dyepig.2019.107826
  • Korolev et al (2020). Fluorescent Nanoagents for Biomedical Applications. Fluorescence Methods for Investigation of Living Cells and Microorganisms. https://doi.org/10.5772/intechopen.92904
  • Zhai et al (2020). An ATF24 peptide-functionalized β-elemene-nanostructured lipid carrier combined with cisplatin for bladder cancer treatment. Cancer Biol & Med. 17(3): 676–692. https://dx.doi.org/10.20892%2Fj.issn.2095-3941.2020.0454
  • Natoni et al (2020). Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model. Haematologia. 105(2): 457–467. https://dx.doi.org/10.3324%2Fhaematol.2018.212266
  • Costa et al (2019). Murine infection with bioluminescent Leishmania infantum axenic amastigotes applied to drug discovery. Sci Reports. 9: 18989. https://doi.org/10.1038/s41598-019-55474-3
  • Ramachandran et al (2019). Non-invasive in vivo imaging of fluorescence-labeled bacterial distributions in aquatic species. Internat'l J Vet Sci Med. 5(2). https://doi.org/10.1016/j.ijvsm.2017.09.003
  • Song et al (2019). Overcoming hypoxia-induced chemoresistance to cisplatin through tumor oxygenation monitored by optical imaging. Nanothernostics. 3(2): 223–235. https://dx.doi.org/10.7150%2Fntno.35935
  • Lorscheider et al (2019). Dexamethasone palmitate nanoparticles: An efficient treatment for rheumatoid arthritis. J Controlled Rel. 296:179-189. https://doi.org/10.1016/j.jconrel.2019.01.015
  • Lazzari et al (2018). Multicellular spheroid based on a triple co-culture: A novel 3D model to mimic pancreatic tumor complexity. Acta Biomaterials. 78: 296-307. https://doi.org/10.1016/j.actbio.2018.08.008
  • Cayre et al (2017). In Vivo FRET Imaging to Predict the Risk Associated with Hepatic Accumulation of Squalene‐Based Prodrug Nanoparticles. Adv. Healthcare Mat. https://doi.org/10.1002/adhm.201700830

Resources

1-6 of 19 Resources
Case Study Icon
Case Study
A novel non-Invasive in vivo tool for the assessment of NASH

Non-alcoholic fatty liver disease (NAFLD) describes a progressive pathology that affects the liver. Fat accumulation causes fatty...

Technical Note Icon
Technical Note
Adaptive Fluorescence Background Subtraction for IVIS systems

Instrument background occurs when excitation light leaks through the emission filter. This occurs more frequently when the...

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Literature - Publication Review
Applications of In Vivo bioluminescence imaging for SARS-CoV-2

Scientists continue to explore several options to treat SARS-CoV-2 infection with hundreds of therapeutics at various phases of...

Article Icon
Article
Assessing nanomedicine delivery across the blood-brain barrier using pre-clinical in vivo imaging

We recently spoke to researchers based at the Centre for Advanced Imaging at the University of Queensland in Australia who have...

Technical Note Icon
Technical Note
AutoExposure

This tech note outlines procedures on using auto-exposure on the IVIS® preclinical optical imaging platform using Living Image®...

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Whitepaper
Bioluminescence Resonance Energy Transfer (BRET) to monitor protein-protein interactions

The ability to image protein-protein interactions (PPIs) in vivo has important implications for a wide variety of biological...

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