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IVIS Lumina III In Vivo Imaging System

The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.

For research use only. Not for use in diagnostic procedures.

Need D-Luciferin substrate in powder or ready-to-use injectable format?

Overview

The IVIS Lumina III is capable of imaging both fluorescent and bioluminescent reporters. The system is equipped with up to 26 filter sets that can be used to image reporters that emit from green to near-infrared. Superior spectral unmixing can be achieved by Lumina III’s optional high resolution short cut off filters.

Features and Benefits

  • Market trusted technology offering the fullest suite of leading imaging technologies, reagents and support
  • Exquisite sensitivity in bioluminescence
  • Full fluorescence tunability through the NIR spectrum
  • Compute Pure Spectrum spectral umixing for ultimate fluorescence sensitivity
  • Expandable system tailored to your workflow

Specifications

Height
104.0 cm
Width
48.0 cm
Brand
IVIS
Imaging Modality
Optical Imaging

References

  • Lim et al (2021). Bioorthogonally surface‐edited extracellular vesicles based on metabolic glycoengineering for CD44‐mediated targeting of inflammatory diseases. J Extracellular Vesicles. https://doi.org/10.1002/jev2.12077
  • Lee et al (2020). NIR dye-loaded mesoporous silica nanoparticles for a multifunctional theranostic platform: Visualization of tumor and ischemic lesions, and performance of photothermal therapy. J Indus. Eng. Chem. 88:99-105. https://doi.org/10.1016/j.jiec.2020.03.027
  • Shim et al (2019). Carrier-free nanoparticles of cathepsin B-cleavable peptide-conjugated doxorubicin prodrug for cancer targeting therapy. Jrnl. Controlled Release. 294: 378-389. https://doi.org/10.1016/j.jconrel.2018.11.032
  • Lee et al (2019). Crushed Gold Shell Nanoparticles Labeled with Radioactive Iodine as a Theranostic Nanoplatform for Macrophage-Mediated Photothermal Therapy. Nano-Micro Letters. 11(36). https://doi.org/10.1007/s40820-019-0266-0
  • Zhang et al (2019). In vivo irreversible albumin-binding near-infrared dye conjugate as a naked-eye and fluorescence dual-mode imaging agent for lymph node tumor metastasis diagnosis. Biomaterials. 217:119279. https://doi.org/10.1016/j.biomaterials.2019.119279
  • Singh et al (2019). A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERRγ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer. Clin Cancer Res. https://doi.org/10.1158/1078-0432.CCR-18-3007
  • Sonoda et al (2018). A Blood-Brain-Barrier-Penetrating Anti-human Transferrin Receptor Antibody Fusion Protein for Neuronopathic Mucopolysaccharidosis II. Mol Ther. 26(2): 1366-1374. https://doi.org/10.1016/j.ymthe.2018.02.032
  • He et al (2018). Repurposing disulfiram for cancer therapy via targeted nanotechnology through enhanced tumor mass penetration and disassembly. Acta Biomater. 28: 113-124. https://doi.org/10.1016/j.actbio.2017.12.023
  • Jung et al (2017). Hydrophobically modified polysaccharide-based on polysialic acid nanoparticles as carriers for anticancer drugs. Int. J Pharmaceutics. 520(1-2): 111-118. https://doi.org/10.1016/j.ijpharm.2017.01.055
  • Kafa et al (2016). Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood–brain barrier in vitro and in vivo. Jrnl. Controlled Release. 225: 217-229. https://doi.org/10.1016/j.jconrel.2016.01.031

Resources

1-6 of 17 Resources
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Literature - Publication Review
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency

Surfactant Protein B (SP-B) deficiency is an uncommon, autosomal recessive lung disorder in term infants. This inability to...

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Case Study
A novel non-Invasive in vivo tool for the assessment of NASH

Non-alcoholic fatty liver disease (NAFLD) describes a progressive pathology that affects the liver. Fat accumulation causes fatty...

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Technical Note
Adaptive Fluorescence Background Subtraction for IVIS systems

Instrument background occurs when excitation light leaks through the emission filter. This occurs more frequently when the...

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Technical Note
AutoExposure

This tech note outlines procedures on using auto-exposure on the IVIS® preclinical optical imaging platform using Living Image®...

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Literature - Publication Review
Bacteria Eat Nanoprobes for Aggregation-enhanced Imaging and Therapy

This study uses a new imaging technique whereby bacteria consume a gold nanoprobe which aggregates intracellularly upon...

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Application Note
Cerenkov Imaging of Radioisotopes in IVIS systems

Optical imaging detects photons in the visible range of the electromagnetic spectrum. PET and SPECT imaging instruments are...

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