Biomarker Discovery
Decode disease at the molecular level
Biomarkers are biological indicators, such as genes, proteins, or other measurable biological characteristics, that can be used to detect, diagnose, or monitor various diseases and health conditions.
Better biomarkers are urgently needed to guide molecularly targeted therapy, monitor therapeutic response, and improve diagnosis across a wide spectrum of disease. The process of biomarker discovery enables researchers to identify these critical indicators.
Revvity offers comprehensive tools for preparing and analyzing samples across diverse biomarker categories. Our biomarker discovery solutions leverage multiplex and multi-omic approaches, empowering you to uncover the molecular signatures of diseases across a wide range of biological samples.
For research use only. Not for use in diagnostics procedures.
Solutions for key biomarker types
Explore our comprehensive solutions for key biomarker types, designed to transform your biomarker discovery and unlock new insights into disease mechanisms. For full project services, our Revvity Omics Services team can collaborate with you to create specialized biomarker assays tailored to your unique research requirements.
DNA and RNA biomarkers
DNA and RNA are powerful biomarkers in research and diagnostics, from gene expression and molecular signatures through treatment prognosis.
DNA and RNA are powerful biomarkers in research and diagnostics, from gene expression and molecular signatures through treatment prognosis.
Revvity offers comprehensive solutions for DNA and RNA (coding and non-coding) biomarker identification, from sample preparation to large-scale automation. These tools facilitate efficient isolation, amplification, and analysis of nucleic acid biomarkers for precision medicine and drug development - supporting next-generation sequencing applications such as single-cell, targeted, and metagenomics sequencing. Additionally, our solutions support the analysis of ctDNA, cfDNA, miRNA, and cfRNA.
Soluble or secreted protein biomarkers
Soluble proteins, such as cytoplasmic proteins and enzymes, and secreted proteins, such as cytokines or antibodies, play important roles in metabolism, signaling, and immune defense.
Soluble proteins, such as cytoplasmic proteins and enzymes, and secreted proteins, such as cytokines or antibodies, play important roles in metabolism, signaling, and immune defense.
Revvity provides biomarker assay solutions including sample homogenizers, microplate readers, immunoassay kits, and reagents for single and multiplex detection of numerous proteins. Choose from different technology platforms depending on your study question, sensitivity, dynamic range and throughput needs.
Single plex protein detection:
Multiplex protein detection:
Quantify up to 14 cytokines or analytes with our bead-based multiplex immunoassays on your flow cytometer.
Instruments:
Workflow automation and software:
Cell surface protein biomarkers
Detection of cell surface proteins is crucial to identify cell types and understand their various cellular functions.
Detection of cell surface proteins is crucial to identify cell types and understand their various cellular functions.
Flow cytometry workflows
Flow cytometry is essential for cell surface protein analysis, providing rapid, multi-parameter data at the single-cell level. Enhance your flow cytometry analysis with BioLegend antibodies.
Utilize surface proteins to isolate and purify cells of interest for downstream analysis. Our magnetic bead-based cell separation system uses antibodies for either positive or negative selection of cells from heterogenous samples.
A crucial step in flow cytometry is the accurate preparation of reagents. Our liquid handling solutions enhance your productivity and support reliable antibody panel preparation.
Using flow cytometry and our lyophilized antibody arrays, you can screen hundreds of cell surface markers on mouse or human cells and determine your target cell antigen profile.
Leverage cloud-based software for real-time visualization of flow cytometry data.
Multiomics
Multiomic analysis integrates various levels of molecular information for deeper biological insights. Our TotalSeq reagents enable simultaneous detection of proteins and RNA or DNA in single-cell sequencing experiments, enhancing multiomic research capabilities.
Tissue biomarkers
Tissue-specific biomarkers that contribute to the organization and heterogeneity of tissues offer deeper insights into disease mechanisms and precision medicine.
Tissue-specific biomarkers that contribute to the organization and heterogeneity of tissues offer deeper insights into disease mechanisms and precision medicine.
By combining the high-resolution molecular profiling of single-cell sequencing with the spatial context provided by spatial biology techniques, researchers can gain a holistic understanding of tissue organization to fuel biomarker discovery.
Our tissue biomarker discovery solutions support researchers in decoding complex cellular landscapes and advancing spatial biology studies.
Spatial omics
Immunofluorescence
Multiplexed/sequential immunofluorescence
Featured resources
Featured blogs
FAQs
-
How do I choose between different biomarker discovery solutions for my specific research needs?
-
Do you offer custom biomarker discovery services?
-
Do you offer automation solutions to streamline biomarker discovery workflows?
-
Do you provide analysis software for biomarker assay data?
