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Next-Generation Biologics

Addressing modern biotherapeutic development challenges with advanced discovery, characterization, and testing solutions

Based on recent progress, next-generation biologics offer the promise to address or treat complex diseases. Success requires innovative solutions to overcome the challenges encountered with these next-generation biologics, including multi-specific antibodies, antibody-drug conjugates (ADCs), and RNA therapeutics / vaccines, to accomplish specificity, efficacy, and safety. This need for innovation has driven the rise in various engineering and modification approaches to standard antibody and RNA modalities for various disorders from cancer and autoimmune diseases to neurological and ophthalmic conditions.

Multi-specific antibodies such as bispecific antibodies (BsAbs) and ADCs provide a more multivalent and precise approach against two or more targets, whilst mRNA vaccines provide flexibility with the ability to efficiently deliver mRNA for rapid uptake.

Improve your next-generation biologics development and characterization with our solutions and products that can support your research in areas of cell line and assay development, tumor cell targeting, ex vivo and in vivo testing, structural and functional characterization, followed by data management and analysis.

For research use only. Not for use in diagnostic procedures.

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Bispecific antibodies

Unlock the power of dual targeting with our BsAb solutions that can help design, engineer, and optimize your antibody therapeutic to target two distinct sites / markers simultaneously for enhanced efficacy and specificity.

Helping you overcome the challenges seen in dual binding, antibody screening, tissue tropism, pharmacodynamics, analysis, and overall complexity within the process.

Products and Platforms

Bioproduction

CHOSOURCE Platform

The CHOSOURCE™ expression platform enables rapid generation of clones expressing high levels of recombinant therapeutic protein during stable cell line development.

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Cell Counting & Image Cytometry Instruments

Revvity offers a leading portfolio of automated cell counters, image cytometry systems, and cell counting reagents and consumables. Together, they provide fast, accurate and efficient ways to assess cell health and viability.

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microplate readers

Microplate Readers

As many of you know, microplate readers are instruments used to detect biological, chemical, biochemical or physical events from samples in a microplate.

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High Content Screening Instruments

High-Content Analysis (HCA) or High-Content Screening (HCS) combines high-throughput automated imaging and analysis to extract quantitative multi-parametric data at the single-cell level.

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Microfluidic Protein Characterization

Proteins differ from each other in their size, molecular structure, and physiochemical properties.

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Cellular Imaging Software

Revvity offers sophisticated cellular imaging and analysis software to help you acquire, visualize, analyze and share your image data more effectively and efficiently, so you can spend more time discovering.

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In Vivo Imaging

Tracking, monitoring, and visualizing biological processes and disease progression is key to not only helping you better understand biology but also crucial in evaluating the effectiveness of your potential drug candidates earlier in the development process.

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immunoassays

Immunoassays

Since their introduction in the 1950's, immunoassays have been an integral part of research and drug discovery.

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Antibody drug conjugates

Revolutionize your therapeutic development with our ADC solutions that can help you discover, develop, and evaluate payload, efficacy and toxicology/safety studies.

Our solutions, including CRISPR tools and screening services, generation of cell models, high-content screening, linker-drug characterization, antibody conjugation, data modelling, potency and detection platforms, and antibody binding and functional assays, can support the precision and reliability required at each stage of your workflow, from discovery through preclinical development.

Products and Platforms

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Antibody Drug Conjugate Services

In the discovery of oncology therapeutics, Antibody-drug conjugates (ADCs) are rapidly gaining momentum, with hundreds of candidates advancing through clinical development.

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Bioproduction

CHOSOURCE Platform

The CHOSOURCE™ expression platform enables rapid generation of clones expressing high levels of recombinant therapeutic protein during stable cell line development.

Learn more
cellometer-ascend-automatic-cell-counter-512x288.png

Cell Counting & Image Cytometry Instruments

Revvity offers a leading portfolio of automated cell counters, image cytometry systems, and cell counting reagents and consumables. Together, they provide fast, accurate and efficient ways to assess cell health and viability.

Learn more
immunoassays

Immunoassays

Since their introduction in the 1950's, immunoassays have been an integral part of research and drug discovery.

Learn more
High Content Screening Instruments thumbnail

High Content Screening Instruments

High-Content Analysis (HCA) or High-Content Screening (HCS) combines high-throughput automated imaging and analysis to extract quantitative multi-parametric data at the single-cell level.

Learn more
microfluidic-protein-characterization-thumbnail-512x288.jpg

Microfluidic Protein Characterization

Proteins differ from each other in their size, molecular structure, and physiochemical properties.

Learn more
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Signals

Simplify data capture, processing, and analysis at each ADC development stage, and identify the most promising antibodies, linkers, and payloads.

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pHSense Reagents

pHSense Reagents

Discover a powerful new plate reader tool specifically designed for cell surface target internalization studies for ADC and GPCR research.

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RNA vaccines and therapeutics

Enhance your RNA therapeutics and vaccine workflows with solutions that can help you produce a safer and efficient approach. With the right support and expertise benefit from the versatility and ease of adaptability a mRNA or other RNA modality platforms can provide.

We can help in target identification, characterization, assay development for early-stage research and screening, as well as preclinical development workflows including evaluation of immunogenicity to support your modality’s efficacy and safety. Our tools and services can address your RNA payload evaluation, optimization and delivery.

Products and Platforms

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Microfluidic Nucleic Acid Analysis

Now you can simplify traditional gel separations, while improving the reproducibility of your data in a fraction of the time.

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Lentivirus

Lentiviruses are a subtype of retroviruses which have a single stranded RNA genome that encode for three major structural genes: gag, pol, and env.

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AAV

Our high-quality premade AAV particles are ideal for pilot studies, or as standardized test material for product, process, or assay development.

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RNA Interference

Dharmacon™ siRNA, shRNA, and microRNA-based reagents, leading the field for nearly 30 years providing highly specific and efficient gene silencing.

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oligonucleotide custom synthesis

Oligonucleotide Custom Synthesis

Leveraging almost 30 years of experience as a leading provider in oligo design and synthesis, Revvity's oligo synthesis team offers a range of services.

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immunoassays

Immunoassays

Since their introduction in the 1950's, immunoassays have been an integral part of research and drug discovery.

Learn more
microplate readers

Microplate Readers

As many of you know, microplate readers are instruments used to detect biological, chemical, biochemical or physical events from samples in a microplate.

Learn more

Featured content

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