Skip to main content

HTRF Human and Mouse Total AP2 Detection Kit, 1000 Assay Points

The total AP2 kit enables the cell-based quantitative detection of AP2, for monitoring GPCR activity.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Part Number: 64AP2TPEB
Unit Size:
Part Number: 64AP2TPEC
Unit Size:
  • The Total AP2 cellular assay monitors total AP2 beta, and is used to detect the expression of endogenous or overexpressed AP2 beta in various cells. AP2 beta are components of the adaptor protein complex 2 (AP-2) and are known to n as cargo proteins. They play several roles in cells, including the internalization of GPCRs through a clathrin-dependent endocytosis process by direct interaction with beta arrestins. ons of AP2 beta ion cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. As AP2 essed in various tissues, it is believed that AP2 may play a major role in many cancers or other human diseases (diabetes) by ing receptor-mediated ns.

  • Assay Points
    1000
    Assay Target Type
    Kit
    Assay Technology
    HTRF
    Brand
    HTRF
    Quantity
    1
    Therapeutic Area
    Cardiovascular
    Inflammation
    Metabolism/Diabetes
    NASH/Fibrosis

Resources

1-1 of 1 Resources
Guide
HTRF solutions, guide to major applications
htrf, guide, application, autoimmunity, cardiology, assays