Homogenizers
Bead mill homogenizers, rotor-stator homogenizer, mixers, and automated homogenizers
With over 65 years of experience, we offer a comprehensive selection of Omni homogenizers that cater to labs with different throughput needs and a range of sample types. Our solutions span from industrial large-volume mixers, handheld rotor stators, and Omni Bead Ruptor™ bead mills for low- to mid-throughput labs all the way through automated homogenizers with liquid handling capabilities for higher-throughput applications.
Homogenizers are versatile laboratory tools in various scientific disciplines. Our solutions are routinely employed for workflows around biological samples, pharmaceutical formulations, food and beverage products. Our solutions can help streamline processes by achieving consistency of homogenization for particle reduction, emulsification of substances such as nanoparticles, and releasing analytes of interest for downstream detection assays.
Explore our comprehensive list of protocol snapshots to plan your sample prep.
For research use only. Not for use in diagnostic procedures.
Choose from our homogenizers for your lab need and industry
Bead Mill Homogenizers
"The [Omni] Bead Ruptor uses a complex motion which we find highly effective. In the past, we have used other types of oscillating machines which have a back-and-forth motion along one dimension which can be a problem with certain sample volumes, such that the sample, beads plus yeast plus buffer, stays in essentially the same place, while the tube oscillates around it."1
Biological and life sciences
Sample homogenizers are widely utilized in biological and life science research for the extraction of proteins, DNA, RNA, and other cellular components They aid in cell disruption, tissue homogenization, and the release of analytes, allowing researchers to study cellular processes, conduct genomic analysis, and explore bio-molecular interactions.
Sample homogenizers are widely utilized in biological and life science research for the extraction of proteins, DNA, RNA, and other cellular components They aid in cell disruption, tissue homogenization, and the release of analytes, allowing researchers to study cellular processes, conduct genomic analysis, and explore bio-molecular interactions.
Check out our popular application notes on extraction of immune mediators/cytokines from skin, comparative RNA extraction data across multiple different sample acquisition/storage parameters on three types of tissues, and metagenomics.
Pharmaceutical and drug development
In the pharmaceutical industry, lab homogenizers are an indispensable resource in formulating pharmaceutical compounds, as well as pushing forward cutting-edge drug development assays.
They facilitate the blending of active pharmaceutical ingredients with excipients, ensuring uniform distribution and particle size reduction for lipid emulsion preparation, and encapsulation of drugs in nano-particle systems. Homogenizers also play a pivotal role in drug-development assays. By enabling a high-throughput and streamlined sample preparation workflow upstream of ADME and DMPK assays, the bottlenecks are eliminated allowing researchers to bring cutting-edge therapeutics to the pre-clinical and clinical markets.
In the pharmaceutical industry, lab homogenizers are an indispensable resource in formulating pharmaceutical compounds, as well as pushing forward cutting-edge drug development assays.
They facilitate the blending of active pharmaceutical ingredients with excipients, ensuring uniform distribution and particle size reduction for lipid emulsion preparation, and encapsulation of drugs in nano-particle systems. Homogenizers also play a pivotal role in drug-development assays. By enabling a high-throughput and streamlined sample preparation workflow upstream of ADME and DMPK assays, the bottlenecks are eliminated allowing researchers to bring cutting-edge therapeutics to the pre-clinical and clinical markets.
In extension with precision medicine and CDx, it is important to leverage in standardization of tough or complex biospecimens for pathogen identification such as in dermatophytes from fingernails or vector-borne diseases from ticks.
Cosmetics and personal care products
Homogenizers play a vital role in formulating cosmetic and personal care products, such as creams, lotions, and emulsions. Similarly, tablets or supplements for wellness purposes can benefit from the consistency in particle size reduction to help investigate the quality and integrity of their production process.
Homogenizers play a vital role in formulating cosmetic and personal care products, such as creams, lotions, and emulsions. Similarly, tablets or supplements for wellness purposes can benefit from the consistency in particle size reduction to help investigate the quality and integrity of their production process.
They ensure the proper dispersion of ingredients, create stable emulsions, and allow for precise control of active ingredient addition. Using a homogenizer also helps to facilitate batch-to-batch consistency by use of programmable/semi-programmable functions on matrices including wet- and dry-grinding of hair.
Food and beverage processing
Homogenization is a key process in the food and beverage industry. Homogenizers help create stable emulsions, prevent separation, and improve product consistency.
They are commonly used in inhomogeneous foodstuff and drink component processing to achieve a smooth texture, prevent separation, and enhance product shelf life. Additionally, homogenizers aid in the production of sauces, dressings, juices, and other liquid-based food products, such as in the decarbonation of soda.
Homogenization is a key process in the food and beverage industry. Homogenizers help create stable emulsions, prevent separation, and improve product consistency.
They are commonly used in inhomogeneous foodstuff and drink component processing to achieve a smooth texture, prevent separation, and enhance product shelf life. Additionally, homogenizers aid in the production of sauces, dressings, juices, and other liquid-based food products, such as in the decarbonation of soda.
Similarly, foods QC processing for traces of pesticide, confectionaries of varying consistencies, and plant materials are but some common applications.
Agriculture
Agriculture - including aquaculture, and forestry - and its practices include precision farming techniques that help enhance efficiency, productivity, and sustainability. Researchers leverage technologies and molecular applications, such as agrigenomics for genotyping and gene-editing/selection, GPS- or GIS- tech to help with crop or livestock monitoring, along with sustainability and environmental-impact surveillance on measurables such as soil health, metagenomics, and the living ecosystem.
Agriculture - including aquaculture, and forestry - and its practices include precision farming techniques that help enhance efficiency, productivity, and sustainability. Researchers leverage technologies and molecular applications, such as agrigenomics for genotyping and gene-editing/selection, GPS- or GIS- tech to help with crop or livestock monitoring, along with sustainability and environmental-impact surveillance on measurables such as soil health, metagenomics, and the living ecosystem.
Homogenizers enable acceleration of tough plant and fibrous materials, common to agricultural workflows such as seeds/nuts, staple crops, and carcass.
Chemical and industrial applications
Homogenizers find applications in various chemical and industrial processes. They assist in particle size reduction, dispersion of pigments and additives in coatings and paints, preparation of stable emulsions for lubricants and fuels, and homogenization of suspensions and slurries.
Homogenizers find applications in various chemical and industrial processes. They assist in particle size reduction, dispersion of pigments and additives in coatings and paints, preparation of stable emulsions for lubricants and fuels, and homogenization of suspensions and slurries.
Homogenizers contribute to improved product quality, consistency, and efficiency in diverse industrial sectors, including robust recovery of analytes from environmental complexes such as soil/clay.
Featured resources
FAQs
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What are homogenizers and how do they work?
Homogenizers help breakdown samples and large particles into smaller particles or substances as a uniform homogenate or mixture. Some homogenizers use mechanical force, such as bead-beating in bead mills or generator probes/high-shear generator probes in rotor-stator homogenizers, while other use high-pressure forces leveraging piston pumps, or ultrasonic frequencies and cavitation – sonicators / ultrasonic homogenizers – to disrupt samples.
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Where are homogenizers commonly used and for what applications?
Homogenizers originated in food processing, such as in homogenizing milk or sauces, before expanding into the field of science and biotechnology within laboratories across basic, transitional, and clinical research. Common applications for lab homogenizers including tissue and cell lysis for DNA / RNA / protein /other small molecule analyte extractions. They also find themselves in workflows related to pharmaceutical formulations for drug discovery/development/manufacturing – cosmetics and personal health products included – within QC applications as well. Food testing and industrial applications such as emulsification are also applications where homogenizers excel to improve workflow efficiency.
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What factors should be considered when choosing homogenizers?
When selecting lab homogenizers, factors such as sample type, volume, desired particle size are all important to consider when exploring your lab’s anticipated common application. These considerations also tie into the homogenization method/technology of choice, together with capacity for top processing speeds, maintenance/durability of the lab equipment, and flexibility in scaling up throughput are all an important part of cost analysis and needs assessment. Automated homogenizers within process workflows for super high-throughput labs also exist for those needing analytical reproducibility afforded by automation.
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What resources do you have for your homogenizers, including combination of bead mill homogenizers and bead-beating cell lysis kits
for different sample types?Refer to our homogenizers protocol snapshot or our resources under Resource Center page by searching Omni Homogenizers & Sonicators under the Product & Services filter.
References:
- Honey, S., & Futcher, B. (2025). A Trizol-Beadbeater RNA extraction method for yeast, and comparison to Novogene RNA extraction. bioRxiv : the preprint server for biology, 2025.07.30.667760.
