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HTRF Human Phospho-RIPK1 (Ser 166) Detection Kit, 10,000 Assay Points

This HTRF kit enables the cell-based quantitative detection of phosphorylated RIPK1 at Ser166 as a readout of the programmed necrotic cell death pathway, also called necroptosis.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Part Number: 64RIPK1S1PEH
Unit Size: 10,000 Assay Points
Part Number: 64RIPK1S1PEG
Unit Size: 500 Assay Points
  • This HTRF cell-based assay conveniently and accurately detects phosphorylated RIPK1 66. RIPK1 (Receptor-Interacting serine/threonine-Protein Kinase 1, also called RIP1 or RIP) is a iator of apoptotic and necrotic cell death, as well as of inflammatory pathways eam of TNFR1 and other receptors. utophosphorylation at Serine 166 is considered to be a biomarker of the initiation of RIPK3/MLKL-dependent necroptosis. roptosis ogrammed necrotic cell death pathway, also called "inflammatory cell death", s closely associated with pathologies including inflammatory and neurodegenerative diseases, as well as cancer. as therefore become an important drug target in the pharmaceutical industry. Therapeutic strategies consist in developing specific small-molecule kinase inhibitors, such as the well-known Necrostatin-1 and Necrostatin-1s.

  • Assay Points
    10000
    Assay Target Type
    Kit
    Assay Technology
    HTRF
    Therapeutic Area
    Inflammation
    Neuroscience
    Oncology & Inflammation
    Brand
    HTRF
    Quantity
    1
    Unit Size
    10,000 Assay Points

Resources

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Guide book
HTRF solutions, guide to major applications
HTRF, guide, application, autoimmunity, cardiology, assays