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IVISense Inflammation Fluorescent Imaging Panel

Enhance your research with fluorescent probes targeting inflammation biology.

Our IVISense Inflammation fluorescent imaging panel enables in vivo visualization and quantification of inflammation biology. The ability to non-invasively quantify inflammation biology in vivo offers greater opportunity for longitudinal studies necessary to better understand disease pathogenesis in the context of intact animal physiology.

For research use only. Not for use in diagnostic procedures.

Part Number: NEV20013
Part Number: NEV20013
  • Inflammation is a complex biological response to stimuli presented by pathogens, tissue damage, or local irritants and involves a variety of immune cells that work to remove and repair the original insult and damaged tissue regions. Our fluorescent imaging probes provide a variety of tools for quantifying inflammatory biology (various proteases or upregulated receptors) as well as detecting and measuring the edema response. The ability to non-invasively quantify inflammation biology in vivo offers greater opportunity for longitudinal studies and understanding disease pathogenesis in the context of intact animal physiology.

    The availability of probes at 680 nm and 750 nm wavelengths further offer the opportunity for multiplex imaging of appropriate probe combinations to maximize information gained from research animals.

  • IVISense inflammation fluorescent imaging panel includes the following six probes
    Part number Fluorescent probe Biological target
    NEV10054EX IVISense Vascular 680 (AngioSense 680EX) Vascular probe:
    Leaks into sites of edema
    NEV10168 IVISense MMP 750 FAST  (MMPSense 750 FAST) Pan-MMP activatable probe:
    Secreted marker of neutrophils, macrophages, and mast cells
    NEV10040  IVISense Folate Receptor 680 (FolateRSense 680) Folate receptor targeted probe:
    Marker on activated neutrophils and macrophages
    NEV10873 IVISense Integrin Receptor 750 (IntegriSense 750) αVβ3 integrin targeted probe:
    Marker on activated macrophages
    NEV11169  IVISense Neutrophil Elastase 680 FAST Neutrophil elastase activatable probe:
    Secreted protease from neutrophils
    NEV11171 IVISense Pan Cathepsin 750 FAST (ProSense 750 FAST) Pan-cathepsin activatable probe:
    Lysosomal marker of a variety of inflammatory cells

     

  • Brand
    IVISense
    Imaging Modality
    Fluorescence
    Optical Imaging Classification
    Fluorescence Imaging
    Quantity in a Package Amount
    6.0 Vials
    Shipping Conditions
    Shipped in Blue Ice
    Therapeutic Area
    Inflammation
    Unit Size
    1 kit containing 6 vials

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