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IVISense Pan Cathepsin 750 Fluorescent Probe (ProSense)

Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time.

Revvity’s IVISense™ Pan Cathepsin fluorescent probes (ProSense®) are versatile pan-cathepsin-activatable NIR agents for imaging various disease-related events. These activatable probes are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation.

For research use only. Not for use in diagnostic procedures.

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SAVE 15% NOW on online orders. Use promo code below.
YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Feature Specification
Unit Size 1 Vial (10 doses)

Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time.

Revvity’s IVISense™ Pan Cathepsin fluorescent probes (ProSense®) are versatile pan-cathepsin-activatable NIR agents for imaging various disease-related events. These activatable probes are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation.

For research use only. Not for use in diagnostic procedures.

Click to copy promo code to clipboard.
SAVE 15% NOW on online orders. Use promo code below.
YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Product Variants
Wave Length: 680 nm
Part #:
NEV10003
List Price
USD 556.29
Wave Length: 750 nm
Part #:
NEV10001EX
List Price
USD 594.55
Wave Length: 750 nm
Style
FAST
Part #:
NEV11171
List Price
USD 656.59

Overview

IVISense Pan Cathepsin 750 is in our family of “Smart” cathepsin probes, which become fluorescent only after enzymatic cleavage, keeping background down and allowing detection of activated protease. It also offers a secondary wavelength for IVISense Pan Cathepsin, to allow greater flexibility for multiplexing with probes of other excitation/emission wavelengths. 24h imaging at 750 nm.

Specifications

Brand
IVISense
Fluorescent Agent Type
Activatable
Imaging Modality
Fluorescence
Shipping Conditions
Shipped in Blue Ice
Therapeutic Area
Arthritis
Atherosclerosis
Inflammation
Oncology/Cancer
Unit Size
1 Vial (10 doses)
Wave Length
750 nm

Resources

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