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AequoZen Human Melanin Concentrating Hormone (MCH1) Cell Line, CHO-K1 Frozen Cells

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.

For research use only. Not for use in diagnostic procedures.
Part Number: ES-370-AF
Part Number: ES-370-AF
  • AequoZen® Double Transfected Cell Lines: melanin concentrating hormone MCH1 receptor, human recombinant, in CHO-K1 host cell. One vial of non-propagatable cells is shipped per order. A detailed technical dossier includes sequence, culture conditions and pharmacological properties of the recombinant receptor. All cell lines are tested for the absence of mycoplasma. Terms and conditions apply. Some products are not available in some countries. Please inquire at your local sales office for more information.

    Features:

    • Ready-to-use cells; no cell culture required (dispense and assay)
    • Fully automatable and miniaturizable to 1536
    • Enables reduction in reagents and consumable costs
    • High signal to background ratio enabling detection of agonists, antagonists and allosteric modulators
    • Robust assay (Z', CV values, solvent resistance)
    • Reduces the number of false positives from autofluorescent compounds in screening libraries
    • Option to work with cells in suspension to increase throughput
    • Amenable for use with calcium coupled ion channels and tyrosine kinase receptors

    AequoZen technology is a generic GPCR technology which can be used with Gs, Gi and Gq coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of the resulting flash luminescence signal.

  • Application
    Drug Discovery & Development
    Assay Validation
    Calcium Luminescence
    Automation Compatible
    Yes
    Brand
    AequoZen
    Host
    CHO-K1
    Shipping Conditions
    Shipped in Dry Ice
    Unit Size
    10 million cells

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