Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
For research use only. Not for use in diagnostic procedures.
AequoZen® Double Transfected Cell Lines: melanin concentrating hormone MCH1 receptor, human recombinant, in CHO-K1 host cell. One vial of non-propagatable cells is shipped per order. A detailed technical dossier includes sequence, culture conditions and pharmacological properties of the recombinant receptor. All cell lines are tested for the absence of mycoplasma. Terms and conditions apply. Some products are not available in some countries. Please inquire at your local sales office for more information.
Features:
AequoZen technology is a generic GPCR technology which can be used with Gs, Gi and Gq coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of the resulting flash luminescence signal.
Application |
Drug Discovery & Development
|
---|---|
Assay Validation |
Calcium Luminescence
|
Automation Compatible |
Yes
|
Brand |
AequoZen
|
Host |
CHO-K1
|
Shipping Conditions |
Shipped in Dry Ice
|
Unit Size |
10 million cells
|
Discover a comprehensive collection of GPCR cell lines, membrane preparations, and complementary radioligands designed to drive...
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