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AequoZen Human Melanin Concentrating Hormone (MCH1) Cell Line, CHO-K1 Frozen Cells

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.

For research use only. Not for use in diagnostic procedures.

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YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Feature Specification
Application Drug Discovery & Development
G-Alpha Coupling Protein 16
G-Alpha Natural Receptor Gq/G11
Validation Calcium Luminescence

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.

For research use only. Not for use in diagnostic procedures.

Click to copy promo code to clipboard.
SAVE 15% NOW on online orders. Use promo code below.
YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Product Variant
Unit Size: 10 million cells
Part #:
ES-370-AF
List Price
USD 1,083.00

Overview

AequoZen® Double Transfected Cell Lines: melanin concentrating hormone MCH1 receptor, human recombinant, in CHO-K1 host cell. One vial of non-propagatable cells is shipped per order. A detailed technical dossier includes sequence, culture conditions and pharmacological properties of the recombinant receptor. All cell lines are tested for the absence of mycoplasma. Terms and conditions apply. Some products are not available in some countries. Please inquire at your local sales office for more information.

Features:

  • Ready-to-use cells; no cell culture required (dispense and assay)
  • Fully automatable and miniaturizable to 1536
  • Enables reduction in reagents and consumable costs
  • High signal to background ratio enabling detection of agonists, antagonists and allosteric modulators
  • Robust assay (Z', CV values, solvent resistance)
  • Reduces the number of false positives from autofluorescent compounds in screening libraries
  • Option to work with cells in suspension to increase throughput
  • Amenable for use with calcium coupled ion channels and tyrosine kinase receptors

AequoZen technology is a generic GPCR technology which can be used with Gs, Gi and Gq coupled GPCRs and calcium coupled ion channels. Following receptor stimulation, increases in intracellular calcium enable measurement of the resulting flash luminescence signal.

Specifications

Application
Drug Discovery & Development
Brand
AequoZen
G-Alpha Coupling Protein
16
G-Alpha Natural Receptor
Gq/G11
Host Cell Line
CHO-K1
Host Species
Human
Receptor
Melanin-Concentrating Hormone
Shipping Conditions
Shipped in Dry Ice
Target Class
GPCR
Unit Size
10 million cells
Validation
Calcium Luminescence

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