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IVISense Osteo 680 Fluorescent Probe (OsteoSense)

Image and quantify osteoporosis, arthritis, cancer metastases, and other bone diseases, as well as normal bone growth and resorption, in vivo with IVISense Osteo Fluorescent Imaging probes (OsteoSense). As opposed to other imaging modalities such as CT or x-ray which raise the risk of harmful irradiation to the subject, in vivo fluorescence imaging offers no radiation exposure concerns, and when performed with optimized hydroxyapatite-targeted probes such as IVISense Osteo, can image and quantify bone growth and elucidate the biology of bone remodeling.

IVISense Osteo probes are available in 3 wavelengths: 680, 750, and 800.

For research use only. Not for use in diagnostic procedures.

For research use only. Not for use in diagnostic procedures.
Part Number: NEV10020EX
Wave Length: 680 nm
Part Number: NEV11105
Wave Length: 800 nm
Part Number: NEV10053EX
Wave Length: 750 nm
  • IVISense Osteo NIR fluorescent bisphosphonate imaging probes are designed to bind with high affinity to hydroxyapatite (HA) both in vivo and in vitro. Since HA is known to bind pyrophosphonates and phosphonates as well as synthetic bisphosphonates with high affinity, IVISense Osteo agents offer a safe and easy way to assess the subtle bone mineral changes that occur in bone growth, bone loss, and in diseases that damage bone, using subtherapeutic doses for imaging.

    IVISense Osteo 680 is excited by 668 ± 10 mn excitation light and emits at 687 ± 10 mn. Including IVISense Isteo 680 in careful experimental design allows for multiplexing with other channels and/or imaging times, and so can be paired with other probes to achieve maximum efficiency and flexibility in imaging.

  • Brand
    IVISense
    Fluorescent Agent Type
    Targeted
    Optical Imaging Classification
    Fluorescence Imaging
    Quantity in a Package Amount
    1.0 Units
    Therapeutic Area
    Arthritis
    Atherosclerosis
    Oncology/Cancer
    Unit Size
    1 Vial (10 doses)
    Wave Length
    680 nm

Resources

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Optimize Bone Imaging Data with IVISense Osteo Probes
OsteoSense, IVISense Osteo, osteo, bone imaging