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IVISense Osteo 680 Fluorescent Probe (OsteoSense)

Image and quantify osteoporosis, arthritis, cancer metastases, and other bone diseases, as well as normal bone growth and resorption, in vivo with IVISense Osteo Fluorescent Imaging probes (OsteoSense). As opposed to other imaging modalities such as CT or x-ray which raise the risk of harmful irradiation to the subject, in vivo fluorescence imaging offers no radiation exposure concerns, and when performed with optimized hydroxyapatite-targeted probes such as IVISense Osteo, can image and quantify bone growth and elucidate the biology of bone remodeling.

IVISense Osteo probes are available in 3 wavelengths: 680, 750, and 800.

For research use only. Not for use in diagnostic procedures.

For research use only. Not for use in diagnostic procedures.

Product Variants
Part number: NEV10020EX
Wave Length: 680 nm
List price: USD 561.46
Your price:
USD 561.46
USD 561.46 /each
Part number: NEV10053EX
Wave Length: 750 nm
List price: USD 561.46
Your price:
USD 0.00
USD 561.46 /each
Part number: NEV11105
Wave Length: 800 nm
List price: USD 562.50
Your price:
USD 0.00
USD 562.50 /each


IVISense Osteo NIR fluorescent bisphosphonate imaging probes are designed to bind with high affinity to hydroxyapatite (HA) both in vivo and in vitro. Since HA is known to bind pyrophosphonates and phosphonates as well as synthetic bisphosphonates with high affinity, IVISense Osteo agents offer a safe and easy way to assess the subtle bone mineral changes that occur in bone growth, bone loss, and in diseases that damage bone, using subtherapeutic doses for imaging.

IVISense Osteo 680 is excited by 668 ± 10 mn excitation light and emits at 687 ± 10 mn. Including IVISense Isteo 680 in careful experimental design allows for multiplexing with other channels and/or imaging times, and so can be paired with other probes to achieve maximum efficiency and flexibility in imaging.


Fluorescent Agent Type
Optical Imaging Classification
Fluorescence Imaging
Quantity in a Package Amount
1.0 Units
Shipping Conditions
Shipped Ambient
Therapeutic Area
Unit Size
1 Vial (10 doses)
Wave Length
680 nm


1-6 of 6 Resources
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Best practices for designing an effective in vivo fluorescence imaging study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into...

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In vivo imaging solutions

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and...

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IVISense fluorescent probe selector guide for oncology research

The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and...

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Application Note
Multiplex 2D imaging of NIR molecular imaging agents on the IVIS SpectrumCT platform

Epifluorescence (2D) imaging of superficially implanted mouse tumor xenograft models offers a fast and simple method for assessing...

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Optimize Bone Imaging Data with IVISense Osteo Probes

IVISense Osteo fluorescent agents optimized and validated hydroxyapatite-targeting probes to image and quantify bone growth and...

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Understanding the ‘how’ and ‘why’ of spectral unmixing

In vivo fluorescence imaging displays a very broad utility and has become a well-established modality for functional imaging in...

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SDS, COAs, Manuals and more

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