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AlphaLISA Human RIG-I Binding Kit, 5,000 Assay Points

The AlphaLISA® Human RIG-I Binding Kit is designed to select and characterize compounds that specifically bind human RIG-I protein.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Part Number: AL3192C
Unit Size:
Part Number: AL3192F
Unit Size:
  • RIG-I (Retinoic acid-Inducible Gene I) is a cytosolic pattern recognition receptor which is known to recognize RNA pathogens in cells. This protein triggers a type 1 interferon response and participates in the innate immune system. By identifying viral dsRNA, the RIG-I protein recognizes infected cells. The N-terminus of RIG-I contacts mitochondrial antiviral signaling proteins after being triggered by a dsRNA, thereby triggering the IFN-1 signaling pathway. Recent studies have shown that RIG-I is also involved in cancer, lupus nephritis, immunoglobulin A nephropathy, Crohn’s disease, and atherosclerosis.

    Formats
    • Our 500 assay point kit allows you to run 500 wells in a 384-well format, using a 20 µL reaction volume (5 µL of sample).
    • Our 5,000 assay point kit allows you to run 5,000 wells in a 384-well format, using a 20 µL reaction volume (5 µL of sample).
    Features
    • No-wash steps, no separation steps
    • ELISA alternative technology
    • Sensitive detection
    • Small sample volume
  • Application
    Protein Binding
    Assay Technology
    Alpha
    Automation Compatible
    Yes
    Brand
    AlphaLISA
    Detection Method
    Alpha
    Experimental Type
    In vitro
    Target Species
    Human
    Therapeutic Area
    Autoimmunity