Thymidine, tritiated on the methyl group. This product is supplied steri-packaged in aqueous solution, and is typically used to label DNA in cell proliferation assays.
For research use only. Not for use in diagnostic procedures.
Feature | Specification |
---|---|
Concentration | 1 mCi/mL |
Label Position | Specifically Labeled |
Molecular Weight | 242.2 |
Thymidine, tritiated on the methyl group. This product is supplied steri-packaged in aqueous solution, and is typically used to label DNA in cell proliferation assays.
For research use only. Not for use in diagnostic procedures.
250 µCi quantity of [Methyl-3H]-Thymidine in aqueous solution is available for your research. Application of [3H]Thymidine can be found in: carboxy-terminal PTH fragments stimulating incorporation in vascular endothelial cells, quantification of granulocyte-macrophage colony-stimulating factor (GM-CSF) hypersensitivity in juvenile myelomonocytic leukemia (JMML), influence of parasympathetic non-adrenergic, non-cholinergic mechanisms on uptake (rat) in response to mastication, measurement of dendritic cell induced T cell response by intracellular ATP levels and uptake in human immunology, etc.
Special Information: If aqueous solutions of thymidine are stored frozen (-20°C), care should be taken to protect the material from U.V. light during the thawing process to prevent possible dimerization.
When [methyl-3H]thymidine is incorporated into cellular DNA and undergoes radiolytic decomposition, [3H]5-hydroxymethyl-2''-deoxyuridine (HMdU) is formed.* The formation of HMdU through transmutation of [methyl-3H]thymidine occurs at the rate of B-decay, which is 0.017% per day. The transmutation product is not volatile.
*References
Concentration |
1 mCi/mL
|
---|---|
Molecular Weight |
242.2
|
Specific Activity |
20.0 Ci/mmol
|
Application |
Drug Discovery & Development
|
---|---|
Brand |
NEN Radiochemicals
|
Buffer/Solvent |
Aqueous solution
|
Detection Modality |
Radiometric
|
Label Position |
Specifically Labeled
|
Packaging |
NENSure vial
|
Radioisotope |
3H
|
Shipping Conditions |
Shipped Ambient
|
Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
|
Storage Conditions |
5°C
|
Unit Size |
250 µCi
|
Are you looking for resources, click on the resource type to explore further.
We are here to answer your questions.