Skip to main content
Menu
US

Thymidine, [Methyl-3H]-, Specific Activity: 2 Ci/mmol, 5 mCi

Thymidine, tritiated on the methyl group. This product is supplied steri-packaged in an aqueous solution, and is typically used in DNA cell proliferation assays.

For research use only. Not for use in diagnostic procedures

Product Variants
Part number: NET027A250UC
Unit Size: 250 µCi
List price: USD 727.54
Your price:
USD 0.00
USD 727.54 /each
Part number: NET027A001MC
Unit Size: 1 mCi
List price: USD 1,305.00
Your price:
USD 0.00
USD 1,305.00 /each
Part number: NET027A005MC
Unit Size: 5 mCi
List price: USD 3,145.00
Your price:
USD 3,145.00
USD 3,145.00 /each

Overview

5 mCi quantity of [Methyl-3H]-Thymidine is available for your research. Application of [3H]Thymidine can be found in: carboxy-terminal PTH fragments stimulating incorporation in vascular endothelial cells, quantification of granulocyte-macrophage colony-stimulating factor (GM-CSF) hypersensitivity in juvenile myelomonocytic leukemia (JMML), influence of parasympathetic non-adrenergic, non-cholinergic mechanisms on uptake (rat) in response to mastication, measurement of dendritic cell induced T cell response by intracellular ATP levels and uptake in human immunology, etc.

Special Information: If aqueous solutions of thymidine are stored frozen (-20°C), care should be taken to protect the material from U.V. light during the thawing process to prevent possible dimerization.

When [methyl-3H]thymidine is incorporated into cellular DNA and undergoes radiolytic decomposition, [3H]5-hydroxymethyl-2''-deoxyuridine (HMdU) is formed.* The formation of HMdU through transmutation of [methyl-3H]thymidine occurs at the rate of B-decay, which is 0.017% per day. The transmutation product is not volatile.

*References

  • S. Apelgot and B. Ekert, J. Chem. Phys. 60, 505 (1963).
  • K. Fink, R. E. Cline, and R. M. Fink, Anal. Chem., 35, 389 (1963).
  • Specifications and Criteria for Biochemical Compounds, Third Edition (ISBN 0-309-01917-6), National Academy of Sciences - National Research Council, Washington, D.C. 1972.
  • G. W. Teebor, K. Frenkel, and M. S. Goldstein, Proc. Natl. Acad. Sci. USA 81, 318 (1984).
  • H. Tono, S.S. Cohen, J. Biol. Chem. 237, 1271 (1962).
  • M. Nemer, J. Biol. Chem. 237, 143 (1962).

Specifications

Molecular Weight
242.2
Application
Molecular Biology
Brand
NEN Radiochemicals
Detection Method
Radiometric
Label Position
Specifically Labeled
Radionuclide
3H
Radioisotope
H-3
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Unit Size
5 mCi

Resources

1-1 of 1 Resources
Calendar Icon
Calendar
2024 Fresh Lot Calendar
SDS, COAs, Manuals and more Illuminator

SDS, COAs, Manuals and more

Are you looking for technical documents for this product. We have housed them in a dedicated section., click on the links below to explore.

Scroll Icon