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Neurotensin, [125I]Tyr3, 10µCi

Neurotensin, labeled with 125I on the tyrosine 3 residue. Neurotensin functions as an agonist at neurotensin receptors. It is known to induce analgesia, hypothermia and increased locomotor activity. Neurotensin is also involved in the regulation of dopamine.

For research use only. Not for use in diagnostic procedures
Product Variants
Part number: NEX198010UC
Unit Size: 10 µCi
List price: USD 1,807.00
Your price:
USD 1,807.00
USD 1,807.00 /each
Part number: NEX198050UC
Unit Size: 50 µCi
List price: USD 5,715.00
Your price:
USD 0.00
USD 5,715.00 /each

Overview

10 µCiQuantities of Neurotensin, [125I]Tyr3are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX198:

  1. Pettibone, D.J., Hess, J.F., Hey, P.J., Jacobson, M.A., Leviten, M., Lis, E.V., Mallorga, P.J., Pascarella, D.M., Snyder, M.A., Williams, J.B., Zeng, Z. (2003), The effects of deleting the mouse neurotensin receptor NTR1 on central and peripheral responses to neurotensin., J Pharmacol Exp Ther, 300 (1): 305-313.

Specifications

Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Detection Method
Radiometric
Fresh Lot Days
Third Monday of each month
Label Position
Nominally Labeled
Radionuclide
125I
Radioisotope
I-125
Receptor Type
Neurotensin
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area
CNS & Neurologic
Inflammation
Pain
Unit Size
10 µCi

Resources

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Calendar
2024 Fresh Lot Calendar
Guide
Iodine-125 handling precautions

This document contains general information designed to provide a basic understanding of radiation safety for Iodine-125. While we...

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