Skip to main content

Histamine Dihydrochloride, [Ring, Methylenes-3H(N)]-, 250µCi (9.25MBq)

Histamine dihydrochloride, tritiated on the ring and methylene groups. Histamine is an endogenous agonist of histamine receptors.

For research use only. Not for use in diagnostic procedures
Part number: NET732250UC
List price: USD 3,548.00
Your price:
USD 3,548.00
USD 3,548.00 /each

Overview

Histamine is the endogenous ligand that binds and activates histamine receptors. These receptors are a class of GPCRs involved in ileum contraction, itching, vasodiluation, bronchoconstriction, and smooth muscle relaxation. Histamine receptors are potential drug targets for asthma, allergy, and cognitive disorders including sleep disorders, Tourette syndrome, Parkinson disease, ADHD, and drug addiction.

We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust.

Specifications

Molecular Weight
184
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Detection Method
Radiometric
Label Position
Nominally Labeled
Radionuclide
3H
Radioisotope
H-3
Receptor Type
Histamine
Shipping Conditions
Shipped Ambient
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area
Gastrointestinal
Inflammation
Metabolic Disorders
Pain
Unit Size
250 µCi

Resources

1-1 of 1 Resources
Calendar
2024 Fresh Lot Calendar
SDS, COAs, Manuals and more Illuminator

SDS, COAs, Manuals and more

Are you looking for technical documents for this product. We have housed them in a dedicated section., click on the links below to explore.

Scroll Icon