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Calcitonin [Tyr22] (salmon), [125I] 10 µCi

NEX423 [125I]-Calcitonin, [Tyr22] (s) is suitable for the use in radioimmunoassay as well as in the radio-receptor assay.

For research use only. Not for use in diagnostic procedures
Part number: NEX423010UC
List price: USD 3,106.00
Your price:
USD 3,106.00
USD 3,106.00 /each

Overview

10 µCi Quantities of Calcitonin [Tyr22] (salmon), [125I] are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX420:

  1. Cascieri, M. A. et al. Mutants of human insulin-like growth factor I with reduced affinity for the type 1 insulin-like growth factor receptor. Biochemistry 27, 3229–3233 (1988).
  2. Chou, Y.-H., Kuo, W.-L., Rosner, M. R., Tang, W.-J. & Goldman, R. D. Structural changes in intermediate filament networks alter the activity of insulin-degrading enzyme. The FASEB Journal 23, 3734–3742 (2009).

Specifications

Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Detection Method
Radiometric
Fresh Lot Days
Fresh upon request
Label Position
Nominally Labeled
Radionuclide
125I
Radioisotope
I-125
Receptor Type
Calcitonin
Shipping Conditions
Shipped Ambient
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area
Angiogenesis
Cardiovascular
Inflammation
Unit Size
10 µCi

Resources

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Guide
Iodine-125 handling precautions

This document contains general information designed to provide a basic understanding of radiation safety for Iodine-125. While we...

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