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α-Bungarotoxin, [125I]-Tyr54-, 50µCi (1.85MBq)

α-bungarotoxin, labeled with 125I on tyrosine residue 54. α-bungarotoxin is a snake venom neurotoxin that acts as an antagonist at nicotinic acetylcholine receptors (nAChRs). This product as offered at two specific activities. Specific activity indicates how much radioactivity there is per molecule of ligand. Several of our 125I-labeled ligands are offered at maximum specific activity (2200 Ci/mmol if one 125I labeling site is available). This indicates that virtually every molecule of ligand provided in the stock vial is radiolabeled.

For research use only. Not for use in diagnostic procedures
Product Variants
Part number: NEX126050UC
Unit Size: 50 µCi
List price: USD 1,017.00
Your price:
USD 1,017.00
USD 1,017.00 /each
Part number: NEX126250UC
Unit Size: 250 µCi
List price: USD 2,996.00
Your price:
USD 0.00
USD 2,996.00 /each
Part number: NEX126500UC
Unit Size: 500 µCi
List price: USD 5,825.00
Your price:
USD 0.00
USD 5,825.00 /each


50 µCi Quantities of α-Bungarotoxin, [125I]-Tyr54- are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX126:

  1. Sekiguchi, K., Imamura, S., Yamaguchi, T., Tabuchi, M., Kanno, H., Terawaki, K., Kase, Y. and Ikarashi, Y. (2011), Effects of yokukansan and donepezil on learning disturbance and aggressiveness induced by intracerebroventricular injection of amyloid β protein in mice. Phytother. Res., 25: 501–507.
  2. Paulo, J.A., Hawrot, E. (2009), Effect of homologous serotonin receptor loop substitutions on the heterologous expression in Pichia of a chimeric acetylcholine-binding protein with α-bungarotoxin-binding activity, Protein Expression and Purification, Volume 67, Issue 2, Pages 76-81.

References for NEX126H:

  1. Strack, S., Khan, M.M., Wild, F. et al. (2015), Turnover of acetylcholine receptors at the endplate revisited: novel insights into nerve-dependent behavior, J Muscle Res Cell Motil 36: 517-524.


Molecular Weight
Drug Discovery & Development
NEN Radiochemicals
Detection Method
Fresh Lot Days
Second Monday of each month
Label Position
Nominally Labeled
Receptor Type
Shipping Conditions
Shipped Ambient
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area
CNS & Neurologic
Unit Size
50 µCi


1-3 of 3 Resources
2024 Fresh Lot Calendar
Literature - Publication Review
Deciphering the properties of neuronal nicotinic acetylcholine receptors using radiolabeled α-Bungarotoxin

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SDS, COAs, Manuals and more Illuminator

SDS, COAs, Manuals and more

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