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StepOne Test


Comprehensive biochemical profiling for over 70 disorders in newborns
stepone

The StepOne® Comprehensive Biochemical Profile is a newborn screening test that can detect more than 70 disorders in newborns from just a few drops of blood. These disorders include Fatty Acid Oxidation Disorders, Organic Acid Disorders, Amino Acid Disorders and other metabolic inherited disorders.

This test screens for Recommended Universal Newborn Screening Panel (RUSP) disorders, which includes the full core and secondary panel recommended by the American College of Medical Genetics and Genomics (ACMG) along with other conditions that may not be found in state-mandated programs. The screening is performed using MS/MS (Tandem Mass Spectrometry) and other technologies.

This testing service has not been cleared or approved by the U.S. Food and Drug Administration. Testing services may not be licensed in accordance with the laws in all countries. The availability of specific test offerings is dependent upon laboratory location. The content on this page is provided for informational purposes only, not as medical advice. It is not intended to substitute the consultation, diagnosis, and/or treatment provided by a qualified licensed physician or other medical professionals.

Expanded Newborn Screen (9)
Step One + SCID + SMA
Test Code NBS020
Turn Around Time 12 days
StepOne + XLAD
Test Code NBS021
Turn Around Time 12 days
StepOne® Comprehensive Biochemical Profile
Test Code B0200
Turn Around Time 3 - 5 days
Step One + SCID + SMA + LSD
Test Code NBS019
Turn Around Time 12 days
LSD 5 Panel
Test Code NBS022
Turn Around Time 12 days
Step one + LSD
Test Code NBS024
Turn Around Time 12 days
NBS 7 Panel + NBS Gold customized
Test Code NBS025
Turn Around Time 12 days

How to order

Step 1

Test selection and place order

Step 2

Specimen collection and shipment

Step 3

Get results

How to order

1. Choose your test

Select the correct test for your patient, and fill out the General Test Requisition Form.

  • Please make sure that all sections are completed, and that the patient has signed an informed consent form.
2. Collect a sample

Obtain a sample for testing from the patient using one of the provided Revvity Omics test packs. If you do not have a kit available in your office, please contact us here and we can have one sent out to your office.

  • Ensure that the patient sample is labeled with the patient’s name and date of birth.
  • Please note that all biochemical assays require a dried blood spot sample.
3. Send a sample

Package the patient sample, informed consent form, and test requisition form back into the test kit, and utilize the included pre-paid shipping label to return the kit to Revvity Omics for processing.

  • We ask that you kindly include any applicable medical records or clinical notes with the sample at the time of test submission.
    FAQs
  • When is the best time to order the StepOne Comprehensive Biochemical Profile?

    Samples for the StepOne comprehensive biochemical profile can be collected between days 2 and 28 of birth.

  • How long does it take to receive the StepOne® biochemical profile results?

    The TAT can vary depending on the type of test selected. In general, the TAT for are 3 days for most biochemical assays.

  • What sample types do you accept?

    All biochemical assays, including the StepOne comprehensive biochemical profile, require a dried blood sample.