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nucleic acid isolation

Nucleic Acid Isolation

Quality automated nucleic acid isolation with chemagic™ technology

Revvity provides a unique and efficient method for isolating nucleic acids based on chemagic technology established over 25 years. With our solution-oriented development that strives to put customers first, we offer high-quality instrumentation, proprietary M-PVA Magnetic Beads and separation technology to ensure consistent nucleic acid quality for all types of downstream applications. Our cross-functional application and automation teams ensure excellent support and a reliable supply of reagents to our customers.

How it works?

The chemagic separation technology involves specific capture of nucleic acids by M-PVA Magnetic Beads that are attracted to transiently magnetized metal rods. The magnetized rods transfer the M-PVA Magnetic Beads through the different process solutions, avoiding potential sample cross-contamination. Rotation of the demagnetized rod heads efficiently resuspends the particles during washing steps. This generates high yields, purity, and low levels of fragmentation of nucleic acids, ensuring success in all types of downstream applications.

Benefits of chemagic nucleic acid purification:

  • Flexible sample volumes (up to 18 ml) with fast run times
  • Proven success with diverse sample types, extraction targets, and downstream applications
  • Reduced risk of cross-contamination
  • High purity and yields of nucleic acids
  • Efficient automated extraction of high molecular weight DNA (> 50 kb)

Chemagic instruments


The chemagic Instruments offer a range of solutions for automated nucleic acid isolation, each designed to meet specific requirements such as sample volume, throughput, and automation needs.

Chemagic kits

chemagic Instruments and Kits offer an innovative and efficient solution for the isolation of high-quality nucleic acids (RNA, miRNA, genomic DNA, cfDNA) from a variety of sample types such as whole blood, serum, plasma, swabs, or saliva. One of the key features of the chemagic Kits is the use of the proprietary M-PVA Magnetic Beads, which are included in all chemagic Kits for DNA and RNA isolation. Furthermore, all chemagic Kits are ready-to-use and contain all the needed plastic materials for automation on chemagic instruments.

For research use only. Not for use in diagnostic procedures.

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