Viral vector engineering and manufacturing for cell and gene therapy
Revvity Gene Delivery, where SIRION Biotech’s expertise lives on supports your cell and gene therapy development process, offering solutions for early R&D all the way to clinical applications, with easy transfer of processes and assays into GMP production.
Whether you need small-scale viral production or full-scale viral vector optimization and manufacture, Revvity Gene Delivery has you covered.
Revvity Gene Delivery supports you through every phase of cell and gene therapy development.
Research and discovery
- Therapeutic payload identification (e.g. microRNA sequences)
- Novel AAV capsid engineering (e.g. AAV Evolution)
- Nanobody targeting
Viral vector development
- Optimized viral vector backbones
- Therapeutic payload cassette optimization
- Lentivirus surface modification technology
Preclinical manufacture
- Upstream and downstream process development (non-GMP)
- Up to 50L AAV manufacturing capacity
- PoC and biodistribution studies of lead candidate batches with a CRO network
GMP alliances
Moving projects from the preclinical phase to a GMP manufacturing facility can require the set up of entirely new processes and analytics. During the early R&D and preclinical project stages at Revvity Gene Delivery, relevant individual project aspects are considered from the start to ensure a seamless clinical project transfer.
Revvity Gene Delivery has developed a global CDMO network over the last 5 years and can recommend and introduce CDMOs worldwide that best suit customer locations and individual project requirements.
Revvity Gene Delivery services accelerate the preclinical phase while developing appropriate upstream and downstream processes and analytic tools to enable a smooth Project Transfer – speeding up the project transfer and process development phase at a CDMO by up to 8 months.
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