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  • CHOSOURCE CLE Services

Bioproduction Cell Line Engineering Services

Help optimize biomanufacturing performance with a custom engineered host cell line

Partner with the right gene editing experts to aid your biotherapeutic development with custom editing of bioproduction cell lines that support your specific manufacturing needs for protein and viral vector therapeutics.

Bringing more than 10 years’ worth of experience in gene editing for biotherapeutic manufacturing and a track record of >70 global regulatory filings, together we can help advance your biotherapeutic research program.

Benefit from:

  • An advanced CRISPR-based platform that helps deliver high efficiency cell line editing with precision and speed, in addition to CRISPR-Cas9 and rAAV technologies
  • Different technology types are available to suit the appropriate edits, targets, and freedom to operate status
  • Editing services are available in established Revvity host cell lines (CHOSOURCE™ expression platform) or any other cell hosts provided by customers (i.e. CHO, HEK, Hela and many more)
  • Capabilities in knock-in of single and multiple genes, knock-out, introduction of landing pads and multiplex gene editing
  • Fully traceable documented history for all commercial cell lines to support IND/CTA filings
  • Various functional validation assays for engineered cell lines available on request
  • Dedicated sales, technical support, and project management teams to assist your cell line editing needs

Bioproduction cell line engineering service workflow

1554101-ILL-Biop-CLE-workflow-image
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The CHOSOURCE™ Platform is available for research, clinical, diagnostic, and commercialization applications under specific licenses from Revvity. The platform is also available for services under a service license from Revvity.

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Featured resources

Brochure

CHOSOURCE™ expression platform

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Whitepaper

Efficient multiplexed targeted gene editing as a strategy to generate improved CHO host cell lines for biotherapeutic manufacturing applications

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Poster

Application of gene editing technologies to improve biotherapeutic manufacturing

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Infographic

Engineering for biotherapeutic production: creating high-performance cell lines

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