PhenoVue™ ROS-570, Total Oxidative Stress Indicator is a cell permeable fluorescent reactive oxygen species indicator and is part of Revvity’s portfolio of cellular imaging reagents. PhenoVue ROS-570, Total Oxidative Stress Indicator exhibits orange fluorescence and is validated for use in imaging microscopy and high-content screening applications. It exhibits a maximum excitation wavelength at 574 nm and a maximum emission wavelength of 588 nm.
View our extensive validation data in the Product Information Sheet within the Resources tab below.
For research use only. Not for use in diagnostic procedures.
Reactive oxygen species (ROS) are naturally produced by all living organisms and participate in cell signaling, gene expression and homeostasis. Increasing levels of ROS is associated with aging, as well as with various diseases such as diabetes, pulmonary disorders, inflammatory diseases, and cancer. ROS are also produced by exogenous sources such as UV or heat. Ultimately elevated ROS concentration, which is known as oxidative stress, results in impairment of membrane lipids, proteins, and nucleic acids.
ROS are reactive molecules which contain oxygen and encompass various entities such as superoxide anion (O2-), hydrogen peroxide (H2O2), hydroxyl radical (•OH), hypochlorous acid (HOCl), peroxynitrite anion (ONOO-), and nitric oxide (NO).
PhenoVue ROS Total Oxidative Stress Indicators, encompassing ROS-490, ROS-570 and ROS-670, enable a myriad of applications as well as multiplexing capability to unravel ROS related biological effects.
PhenoVue ROS-570, Total Oxidative Stress Indicator is a nonfluorescent cell-permeable probe which emits bright orange fluorescence upon reaction with hydroxyl radical, hydrogen peroxide and hypochlorite anion.
Features:
Equivalent Number of Microplates:
Color |
Orange
|
---|
Application |
High Content Imaging
Microscopy
|
---|---|
Brand |
PhenoVue™
|
Detection Modality |
Fluorescence
|
Filter |
Cy3/TRITC
|
Quantity |
1 x 1 mg
|
Sample Type |
Live samples only
|
Shipping Conditions |
Shipped in Dry Ice
|
Storage Conditions |
-16 °C or below, protected from light
|
Type |
Individual Reagent
|
This flyer describes Revvity's PhenoVue cellular imaging reagents.
This is a product information sheet for Phenovue ROS, Total Oxidative Stress Indicators
This is a product information sheet for Phenovue ROS, Total Oxidative Stress Indicators
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