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HTRF Mouse Total STING Detection Kit, 500 Assay Points
HTRF Mouse Total STING Detection Kit, 500 Assay Points
The Mouse Total STING kit is designed to monitor the expression level of cellular mouse STING, and can be used as a normalization assay for the Mouse phospho-STING kit.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
| Feature | Specification |
|---|---|
| Application | Cell Signaling |
| Sample Volume | 16 µL |
The Mouse Total STING kit is designed to monitor the expression level of cellular mouse STING, and can be used as a normalization assay for the Mouse phospho-STING kit.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
HTRF Mouse Total STING Detection Kit, 500 Assay Points
HTRF Mouse Total STING Detection Kit, 500 Assay Points
Product information
Overview
The Mouse Total STING cellular assay monitors mouse total STING, and can be used as a normalization assay with the Mouse Phospho STING kit. This kit is compatible with the buffers from the Mouse Phospho STING kit, so the same lysate can be used for analyses of both the phosphorylated and the total protein populations.
Following pathogen infection and binding of dsDNA to the cytoplasmic sensor cGAS, STING protein is phosphorylated by TBK1. This enables, its binding to IRF3 which induces IFNs type 1 production and other immune responses. The STING pathway is then switched off by STING degradation involving autophagy.
Specifications
| Application |
Cell Signaling
|
|---|---|
| Brand |
HTRF
|
| Detection Modality |
HTRF
|
| Lysis Buffer Compatibility |
Lysis Buffer 1
Lysis Buffer 2
Lysis Buffer 3
Lysis Buffer 4
|
| Molecular Modification |
Total
|
| Product Group |
Kit
|
| Sample Volume |
16 µL
|
| Shipping Conditions |
Shipped in Dry Ice
|
| Target Class |
Phosphoproteins
|
| Target Species |
Mouse
|
| Technology |
TR-FRET
|
| Unit Size |
500 Assay Points
|
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HTRF Mouse Total STING Detection Kit, 500 Assay Points
HTRF Mouse Total STING Detection Kit, 500 Assay Points
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