Revvity Sites Globally
Select your location.
*e-commerce not available for this region.
HTRF IBMX Phosphodiesterase Inhibitor, 40 µL
HTRF IBMX Phosphodiesterase Inhibitor, 40 µL
IBMX is a phosphodiesterase inhibitor to be used in the cAMP Gs and cAMP Gi kits. IBMX guarantees cAMP accumulation in the cytoplasm.
| Feature | Specification |
|---|---|
| Application | Second Messenger Detection |
IBMX is a phosphodiesterase inhibitor to be used in the cAMP Gs and cAMP Gi kits. IBMX guarantees cAMP accumulation in the cytoplasm.
HTRF IBMX Phosphodiesterase Inhibitor, 40 µL
HTRF IBMX Phosphodiesterase Inhibitor, 40 µL
Product information
Overview
PDEs are represented by a large super-family of enzymes whose role is to hydrolyze cAMP into AMP, and cGMP into GMP. It should be emphasized that while not all PDEs lead to the specific hydrolysis of cAMP, the non-selective PDE inhibitor IBMX is often the preferred chemical used in most cAMP accumulation assays.
The use of a Pan-PDE inhibitor ensures that the hydrolysis effect of most PDEs will be inhibited, which in turn guarantees high levels of cAMP accumulation in the cell.
Specifications
| Application |
Second Messenger Detection
|
|---|---|
| Brand |
HTRF
|
| Detection Modality |
HTRF
|
| Product Group |
Buffer
|
| Shipping Conditions |
Shipped Ambient
|
| Target Class |
GPCR
|
| Technology |
TR-FRET
|
| Therapeutic Area |
Cardiovascular
Infectious Diseases
Metabolism/Diabetes
NASH/Fibrosis
Neuroscience
Oncology & Inflammation
Rare Diseases
|
| Unit Size |
40 assay points
|
Video gallery
HTRF IBMX Phosphodiesterase Inhibitor, 40 µL
HTRF IBMX Phosphodiesterase Inhibitor, 40 µL
Resources
Are you looking for resources, click on the resource type to explore further.
G-protein coupled receptors (GPCRs) are crucial transmembrane proteins involved in cellular signal transduction.
This technical...
Discover the versatility and precision of Homogeneous Time-Resolved Fluorescence (HTRF) technology. Our HTRF portfolio offers a...
This guide provides you an overview of HTRF applications in several therapeutic areas.
How can we help you?
We are here to answer your questions.
