HTRF Human PCSK9 Detection Kit, 500 Assay Points

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HTRF Human PCSK9 Detection Kit, 500 Assay Points

SDS

IFUs, Manuals & more

The Human PCSK-9 kit is designed for the rapid quantification of Proprotein convertase subtilisin/kexin type 9 in cell supernatants.

Product information

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

SDS

IFUs, Manuals & more

Product Variants

partnumber

Part number: 63ADK050PEG

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Unit Size: 500 Assay Points

List price: USD 1,086.00

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USD 1,086.00

USD 1,086.00 /each

partnumber

Part number: 63ADK050PEH

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Unit Size: 10,000 Assay Points

List price: USD 12,280.00

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USD 0.00

USD 12,280.00 /each

Product information

Overview

PCSK-9 (proprotein convertase subtilisin/kexin type 9) is a member of the proprotein convertase family that plays an important role in lipoprotein homeostasis. PCSK9 binds to the receptor for low-density lipoprotein particles (LDLR) within extracellular fluid, triggering ingestion of LDL-particles into cells. PCSK9 blocking can lower blood LDL-particle concentrations. The PCSK-9 kit is designed for the detection of proprotein convertase subtilisin/kexin type 9 directly in cell supernatants.

Specifications

Other Specifications

Assay Points	500
Assay Target Type	Kit
Assay Technology	HTRF
Brand	HTRF
Quantity	1
Shipping Conditions	Shipped in Dry Ice
Therapeutic Area	Cardiovascular Metabolism/Diabetes
Unit Size	500 Assay Points

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How it works

Assay principle

Human PCSK-9 is measured using a sandwich immunoassay involving two specific human PCSK-9 antibodies, respectively labelled with Europium Cryptate (donor) and d2 (acceptor). The intensity of the signal is proportional to the concentration of PCSK-9 present in the sample.

Assay Protocol

The PCSK-9 assay features a streamlined protocol with only one incubation step following the sample/calibrator and Antibody conjugates dispensing. The antibodies labelled with HTRF donor and acceptor may be pre-mixed and added in a single dispensing step to further streamline the assay procedure. This protocol requires a single 2-hour incubation period at RT.