| Feature | Specification |
|---|---|
| Application | Second Messenger Detection |
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Forskolin activates the adenylyl cyclase enzyme and increases the intracellular level of cAMP. It is used as a positive control for Gs applications ( biological models validation, maximal intracellular cAMP modulation determination). It is highly used for Gi coupled receptor study as a pre-activation step to reveal a cAMP inhibition upon cell stimulation.
| Application |
Second Messenger Detection
|
|---|---|
| Brand |
HTRF
|
| Detection Modality |
HTRF
|
| Product Group |
Buffer
|
| Shipping Conditions |
Shipped Ambient
|
| Target Class |
GPCR
|
| Technology |
TR-FRET
|
| Therapeutic Area |
Cardiovascular
Infectious Diseases
Metabolism/Diabetes
NASH/Fibrosis
Neuroscience
Oncology & Inflammation
Rare Diseases
|
| Unit Size |
40 assay points
|
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