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This biochemical assay format enables the detection of the interaction between a subset of epigenetic binding domains and modified histone sequences.
The EPIgeneous Binding Domain kit series provides a simple biochemical approach to study epigenetic reader domain interactions with modified histones. All kits are based on a GST-tagged binding domain / biotin-coupled Histone peptide format, and can be run using the same add-and-read single plate protocol.
Binding Domain kit C has been successfully validated on 4 different domains, including some important therapeutic targets, in the BRD and ATAD families.
|Assay Target Type
Oncology & Inflammation
10,000 Assay Points