The AlphaLISA™ SureFire® Ultra™ Human and Mouse Phospho-RAB 8A (Thr72) assay is a sandwich immunoassay for quantitative detection of phospho-RAB 8A (Thr72) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Ras-related protein RAB8A is a member of the RAS superfamily, which consists of small GTP/GDP binding proteins. Small GTPases Rab are key regulators of intracellular membrane trafficking, including the formation of transport vesicles to their fusion with membranes. RAB8A is involved in polarized vesicular trafficking and neurotransmitter release. RAB8A is associated with selective autophagy. Rab8a is one of several Rab GTPases that are substrates of leucine-rich repeat kinase 2 (LRRK2), a serine/threonine kinase that is linked to Parkinson's disease.
The AlphaLISA SureFire Human and Mouse Phospho-RAB 8A (Thr72) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-RAB 8A (Thr72) in cellular lysates, using Alpha Technology.
Application |
Cell Signaling
|
---|---|
Assay Target |
RAB 8A
|
Assay Target Class |
Phosphoproteins
|
Assay Technology |
Alpha
|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Molecular Modification |
Phosphorylation
|
Product Group |
Kit
|
Sample Volume |
10 µL
|
Shipping Conditions |
Shipped in Blue Ice
|
Target Species |
Human
Mouse
|
Therapeutic Area |
Neuroscience
|
Unit Size |
500 Assay Points
|
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