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AlphaLISA SureFire Ultra Human and Mouse Phospho-LRRK2 (Ser910) Detection Kit, 50,000 Assay Points

The AlphaLISA® SureFire® Ultra Human and Mouse Phospho-LRRK2 (Ser910) assay is a sandwich immunoassay for quantitative detection of phospho-LRRK2 (Ser910) in cellular lysates using Alpha Technology.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

Product Variants
Part number: ALSU-PLRRK2-C500
Unit Size: 500 Assay Points
List price: USD 2,346.00
Your price:
USD 0.00
USD 2,346.00 /each
Part number: ALSU-PLRRK2-C10K
Unit Size: 10,000 Assay Points
List price: USD 14,270.00
Your price:
USD 0.00
USD 14,270.00 /each
Part number: ALSU-PLRRK2-C50K
Unit Size: 50,000 Assay Points
List price: USD 46,060.00
Your price:
USD 46,060.00
USD 46,060.00 /each
Part number: ALSU-PLRRK2-C-HV
Unit Size: 100 Assay Points
List price: USD 694.44
Your price:
USD 0.00
USD 694.44 /each

Overview

Leucine-rich repeat kinase 2, also known as LRRK2, Dardarin, or PARK8, is a member of the ROCO superfamily and is a large, multifunctional kinase enzyme. The ROCO family characteristics include the presence of a tandem Ras of complex (Roc) G-domain, kinase domains, and carboxy- terminal of Roc (COR) sequence which links them. LRRK2 modulates Tau phosphorylation via GSK-3b and is involved in lysosomal function and the innate immunity in the brain (microglia activation). Mutations observed in LRRK2 have been associated with Parkinson’s disease.

The AlphaLISA SureFire Human and Mouse Phospho-LRRK2 (Ser910) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-LRRK2 (Ser910) in cellular lysates, using Alpha Technology.

Formats
  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
AlphaLISA SureFire Ultra kits are compatible with
  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies
Alpha SureFire kits can be used for
  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Application
Protein Detection
Assay Technology
Alpha
Automation Compatible
Yes
Brand
AlphaLISA SureFire Ultra
Detection Method
Alpha
Experimental Type
In vitro
Target Species
Human
Mouse
Therapeutic Area
Neuroscience
Unit Size
50,000 Assay Points

Video gallery

Resources

1-4 of 4 Resources
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Guide
AlphaLISA SureFire Ultra assay optimization

This guide outlines further possible optimization of cellular and immunoassay parameters to ensure the best possible results are...

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Brochure
Alpha SureFire Ultra no-wash immunoassay catalog

Discover Alpha SureFire® Ultra™ assays, the no-wash cellular kinase assays leveraging Revvity's exclusive bead-based technology...

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Application Note
Characterizing Chemokine Receptor Inhibitors with AlphaLISA SureFire Ultra

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Guide
Download your guide about neurodegenerative diseases

Emerging pathways to neuroinflammation and neurodegeneration

Neurodegenerative diseases, such as amyotrophic lateral sclerosis...

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SDS, COAs, Manuals and more

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