Skip to main content

AlphaLISA SureFire Ultra Human and Mouse Phospho-LRRK2 (Ser910) Detection Kit, 500 Assay Points

The AlphaLISA® SureFire® Ultra Human and Mouse Phospho-LRRK2 (Ser910) assay is a sandwich immunoassay for quantitative detection of phospho-LRRK2 (Ser910) in cellular lysates using Alpha Technology.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Part Number: ALSU-PLRRK2-C500
Unit Size:
Part Number: ALSU-PLRRK2-C10K
Unit Size:
Part Number: ALSU-PLRRK2-C50K
Unit Size:
Part Number: ALSU-PLRRK2-C-HV
Unit Size:
  • Leucine-rich repeat kinase 2, also known as LRRK2, Dardarin, or PARK8, is a member of the ROCO superfamily and is a large, multifunctional kinase enzyme. The ROCO family characteristics include the presence of a tandem Ras of complex (Roc) G-domain, kinase domains, and carboxy- terminal of Roc (COR) sequence which links them. LRRK2 modulates Tau phosphorylation via GSK-3b and is involved in lysosomal function and the innate immunity in the brain (microglia activation). Mutations observed in LRRK2 have been associated with Parkinson’s disease.

    The AlphaLISA SureFire Human and Mouse Phospho-LRRK2 (Ser910) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-LRRK2 (Ser910) in cellular lysates, using Alpha Technology.

    Formats
    • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
    • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
    • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
    • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
    AlphaLISA SureFire Ultra kits are compatible with
    • Cell and tissue lysates
    • Antibody modulators
    • Biotherapeutic antibodies
    Alpha SureFire kits can be used for
    • Cellular kinase assays
    • Receptor activation studies
    • Screening
  • Application
    Protein Detection
    Assay Technology
    Alpha
    Automation Compatible
    Yes
    Brand
    AlphaLISA SureFire Ultra
    Detection Method
    Alpha
    Experimental Type
    In vitro
    Target Species
    Human
    Mouse
    Therapeutic Area
    Neuroscience

Resources

1-1 of 1 Resources
Application Note Icon Image
Application Note
Characterizing Chemokine Receptor Inhibitors with AlphaLISA SureFire Ultra
surefire, neutralizing antibody, neutralizing antibodies, biotherapeutics, biotx