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Vanadis NIPT System

Easy. Precise. Cost-effective.

Vanadis® NIPT system is an automated cell-free DNA testing platform designed to make noninvasive prenatal testing accessible to more women – and more cost-effective for your laboratory.


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PERSPECTIVES ON VANADIS

Customer experiences with Vanadis NIPT

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WORKFLOW

Streamlined workflow from primary tube to final result

Screen for the risk of trisomies 21, 18, 13, as well as fetal sex determination with Vanadis NIPT. By targeting thousands of chromosomal sequences, the Vanadis system can bring high precision non-invasive prenatal testing to your lab, counting an average of 650,000 molecules per chromosome.

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Walkaway automation for greater efficiency

With Vanadis technology, all the critical steps are automated, starting with pipetting steps to reduce manual errors. Plasma volumes are monitored by camera to avoid contamination by the buffy coat, and samples and reagents are barcoded for complete tracking throughout the workflow. Our software guides you through the process, with user-friendly touchscreens, enabling remote workflow management for ease of use. Easy to integrate, our software is designed for LIMS connectivity, reducing manual errors while simplifying data management.

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GROUNDBREAKING cfDNA TECHNOLOGY

No PCR, No sequencing

Vanadis is the only NIPT screening platform to enable targeted cfDNA analysis without PCR, instead directly capturing target fragments and labeling them for counting. A proprietary nanofilter plate then captures labeled molecules for imaging, eliminating the need for data-intensive steps such as DNA sequencing, microarrays, and microfluidics.

Benefits for your laboratory

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Easy to use. Easy to learn

Walkaway automation minimizes hands-on time and allows for quicker test results, available within 2-3 days.

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Scalable platform

Requiring only a single technician to run up to 14 000 samples per year, Vanadis empowers laboratories under ever-increasing workloads.

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High-precision technology

Designed to deliver high-precision measurements to improve the detection and false positive rates while minimizing the no-call rate.

KITS

Proven clinical performance

Clinical studies have demonstrated that the Vanadis NIPT system could improve detection and false positive rates, while minimizing the number of no-calls.

Products comprising the Vanadis NIPT system are CE-marked in vitro diagnostic products in accordance with European directive 98/79/EC.

 

Trisomy 21

Trisomy 18

Trisomy 13

Detection Rate (95% CI)

100%

(80/80)

(95.5%-100%)

91.4%

(32/35)

(76.9%-98.2%)

100%

(10/10)

(69.2%-100%)

False Positive Rate (95% CI)

0.0%

(0/666)

(0.0%-0.6%)

0.2%

(2/1033)

(0.0%-0.7%)

0.1%

(1/1033)

(0.0%-0.5%)

The observed no-call rate: 0.94% (after first pass)


Source: Vanadis kit insert, version 4

SOFTWARE

Leading risk calculation software

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LifeCycle™ software

Vanadis™ NIPT system includes System Software and trusted LifeCycle™ software, the complete data management solution for prenatal screening laboratories. With a simple and flexible user interface and a performance monitoring dashboard that enables access from any current Web browser, these software provide the reliability and support laboratories can rely on.

Learn more about LifeCycle™
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