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PhenoVue anti-Phospho H2AX (S139) - Mouse IgG1 Antibody, 100x
PhenoVue anti-Phospho H2AX (S139) - Mouse IgG1 Antibody, 100x
HeLa cells treated with etoposide followed by staining with the PhenoVue DNA damage response staining kit. γH2AX (phospho S139 H2AX) is shown in green and 53BP1 in red.
The PhenoVue™ anti-Phospho H2AX (S139) - mouse IgG1 antibody, part of the PhenoVue DNA Damage Response Staining Kit (PDDR11), supports imaging and high-content analysis.
The PhenoVue™ anti-Phospho H2AX (S139) - mouse IgG1 antibody, part of the PhenoVue DNA Damage Response Staining Kit (PDDR11), supports imaging and high-content analysis.
Product variant
Quantity: 1 x 100 µL
Part #:
PAMS139H2AX11
List price
USD 250.00
Your price:
For research use only. Not for use in diagnostic procedures.
PhenoVue anti-Phospho H2AX (S139) - Mouse IgG1 Antibody, 100x
HeLa cells treated with etoposide followed by staining with the PhenoVue DNA damage response staining kit. γH2AX (phospho S139 H2AX) is shown in green and 53BP1 in red.
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Product information
Overview
DNA damage ranges from single-strand breaks (SSBs) to double-strand breaks (DSBs) and complex base modifications. DSBs are the most harmful, leading to genomic instability or cell death if unrepaired. Cells activate the DNA damage response (DDR) to detect and repair damage, crucial for studying genome stability, assessing cytotoxic agents, and developing anticancer drugs.
γ-H2AX (phosphorylated H2AX on Ser139) serves as a key biomarker of DSBs, as its rapid phosphorylation at damage sites is essential for DDR activation. The PhenoVue anti-Phospho H2AX (S139) - mouse IgG1 antibody, part of the PhenoVue DNA Damage Response Staining Kit (PDDR11), supports imaging and high-content analysis applications.
Specifications
| Form |
Solution
|
|---|
| Application |
High Content Imaging
Microscopy
|
|---|---|
| Assay Points |
1 x 384-well microplate
|
| Brand |
PhenoVue™
|
| Host Species |
Mouse
|
| Product Group |
Antibody
|
| Quantity |
1 x 100 µL
|
| Sample Type |
Fixed samples only
|
| Shipping Conditions |
Shipped in Dry Ice
|
| Storage Conditions |
-16 °C or below, protected from light
|
| Target Species |
Human
Mouse (predicted)
|
| Type |
Individual reagent
|
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