Choose your perfect level of automation
Only one single primary blood tube is needed throughout the T-SPOT.TB workflow
Cell isolation - A range of options to match your workflow
Isolate & wash PBMCs using +ve selection
Auto-Pure 10B
Auto-Pure 20B
Auto-Pure 24
Auto-Pure 2400
Cell counting
Enumerate isolated PBMCs
Cellaca MX High-Throughput Cell Counter
Plate preparation
Normalise & plate PBMCs
Auto-Pure 2400
Janus G3
Revvity offer a range of plate preparation platforms:
Plate development
Wash and add substrate & conjugate
Janus G3
Revvity offer a range of plate preparation platforms:
Review T-Cell produced interferon gamma spots
Microwell Imager
Microwell Imager
NEW: Auto-Pure 2400 - CE IVD and FDA approved
Designed for testing up to 24 samples per run, the Auto-Pure 2400 is an automated liquid handling platform with integrated cell isolation technology.
The Auto-Pure 2400 can perform day one T-SPOT.TB workflows in under 3.5 hours with a single mid-run user interaction.
- Efficient workflow, more time for you.
- Easy to use, easy to get right.
- Access high-quality testing, be confident in the result.
Less than 10 mins hands-on time once the Auto-Pure 2400 workflow has commenced*
Benefits at a glance
Only one single primary tube needed**
Room temperature (18° – 25°C) sample storage1
54-hour sample stability2
Low indeterminate results, few repeat tests4
Maintains performance in the immunosuppressed5,6
High sensitivity and specificity providing accurate results1
Case study
Watch now: When the UK's national TB reference laboratory needed to scale without sacrificing quality, they turned to automation. Hear how Oxford Diagnostic Laboratories uses the Auto-Pure 2400 to help process 400+ samples a day, freeing expert technicians to focus on what matters most.
Case study
Medical Centre for Infectious Diseases Berlin (MIB) improves TB detection in immunosuppressed patients with the T-SPOT.TB test and automated ELISPOT workflow
Hear from our customers
Expert Panel: Clinical experts share real-world T-SPOT.TB implementation experiences, featuring Portuguese guideline updates and Auto-Pure 2400 automation success from INSA Lisbon.
“We have been convinced users of the T-SPOT.TB test for many years and are very satisfied with the performance and results, especially in patients with immunosuppression.
The new automation solutions not only enable more flexible sample logistics and laboratory organisation but also lead to a higher cell yield with consistently high cell quality.”
Dr Martin Obermeier
Director and Head of Laboratory
MIB -Medical and Infectious Diseases Centre Berlin
"The implementation of the Auto-Pure 2400 with the T-SPOT.TB test has already yielded some exciting results, with zero occurrences of low PBMC rates (insufficient cells) and 100% result concordance across testing. This data includes samples received from immunosuppressed individuals"
Elliot Derby
Technical Scientist
Oxford Diagnostic Laboratories (Trading division of Oxford Immunotec Limited, a Revvity company)
Expert demo previews
Meet our T-SPOT automation specialists as they give you a sneak peek into our cutting-edge solutions
Watch James demonstrate the Auto-Pure 2400 in action with the T-SPOT.TB
test. This lab-based teaser shows how our automation solution
streamlines the testing process, improving efficiency
and consistency in your TB testing workflow
Join Yasmin at ESCMID as she walks through the complete T-SPOT.TB workflow on the Auto-Pure 2400 platform. See first-hand how this integrated solution transforms laboratory operations from sample
preparation to results analysis
Explore our T-SPOT related solutions
Reference
- Oxford Immunotec T-SPOT.TB Package Insert PI-TB-IVD-UK-v7. Abingdon, UK. September 2024.
- T-Cell Select Package Insert PI-TS-IVD-UK-V9 Abingdon, UK. September 2024. T-Cell Select Package Insert PI-TS-IVD-US v6. Abingdon, UK. March 2025.
- Wang SH etal. Novel Automation of an Enzyme-Linked Immunosorbent Spot Assay Testing Method: Comparable Diagnostic Performance of the T-SPOT.TB Test Using Manual Density Gradient Cell Isolation versus Automated Positive Selection with the T-Cell Select Kit. J Clin Microbiol. 2022 Sep 21;60(9):e0055122. doi: 10.1128/jcm.00551-22. Epub 2022 Aug 30. PMID: 36040150; PMCID: PMC9491199.
- Rego K, et al. Utility of the T-SPOT®.TB test’s borderline category to increase test resolution for results around the cut-off point. Tuberculosis. 2018;108:178
- Wong SH, Gao Q, Tsoi KK, Wu WK, Tam LS, Lee N, Chan FK, Wu JC, Sung JJ, Ng SC. Effect of immunosuppressive therapy on interferon γ release assay for latent tuberculosis screening in patients with autoimmune diseases: a systematic review and meta-analysis. Thorax. 2016 Jan
- Clark SA, Martin SL, Pozniak A, et al. Tuberculosis antigen-specific immune responses can be detected using enzyme-linked immunospot technology in human immunodeficiency virus (HIV)-1 patients with advanced disease. Clin Exp Immunol. 2007;150(2):238-244.
*Mid run user intervention with Auto-Pure 2400 workflow with Cellaca MX
**In immunosuppressed individuals two tubes may be requested
The T-SPOT™ automation workflow is open for lab-selected cell counting and plate imaging. Please refer to the instructions for use for product-specific disclaimers.
For in vitro diagnostic use. This product is only available where licensed in accordance with the law. Please contact your local representative for availability.
Copyright ©2026, Revvity, Inc. All rights reserved. Revvity is a trademark of Revvity, Inc. All other trademarks are the property of their respective owners.
