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Orexin A, [125I]-, 50µCi (1.85MBq)

Orexin A, labeled with 125I. Orexin A binds to orexin receptors (OX1 and OX2), which are potential drug targets for sleep disorders.

For research use only. Not for use in diagnostic procedures.

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Feature Specification
Fresh Lot Days Second Monday of each month
Label Position Nominally Labeled
Molecular Weight ~3562
Receptor Orexin

Orexin A, labeled with 125I. Orexin A binds to orexin receptors (OX1 and OX2), which are potential drug targets for sleep disorders.

For research use only. Not for use in diagnostic procedures.

Click to copy promo code to clipboard.
SAVE 15% NOW on online orders. Use promo code below.
YEAREND15
Offer valid until 12/15. Terms and conditions apply.
Product Variants
Unit Size: 10 µCi
Part #:
NEX367010UC
List Price
USD 2,053.00
Unit Size: 50 µCi
Part #:
NEX367050UC
List Price
USD 6,375.00

Overview

50 µCi Quantities of Orexin A, [125I]- are available for your research.

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, Revvity has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX367:

  1. Wieland, H. A., Söll, R. M., Doods, H. N., Stenkamp, D., Hurnaus, R., Lämmle, B. and Beck-Sickinger, A. G. (2002), The SK-N-MC cell line expresses an orexin binding site different from recombinant orexin 1-type receptor. European Journal of Biochemistry, 269: 1128–1135.

Specifications

Molecular Weight
~3562
Specific Activity
2200.0 Ci/mmol
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
20% acetonitrile in 0.1M Tris HCl pH 7.5 and 0.1% BSA
Detection Modality
Radiometric
Fresh Lot Days
Second Monday of each month
Label Position
Nominally Labeled
Packaging
NENSure vial
Radioisotope
125I
Receptor
Orexin
Shipping Conditions
Shipped in Dry Ice
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
-20°C
Therapeutic Area
Gastrointestinal
Metabolic Disorders
Unit Size
50 µCi

Resources

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