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EnVision XCite Multimode Plate Reader

The EnVision XCite multimode plate reader provides exceptional sensitivity across all detection technologies, while keeping you flexible with both filter and monochromator based options plus full upgradeability.

And, the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP).

For research use only. Not for use in diagnostic procedures.
Part Number: 2105-0010
  • Winner of SelectScience® Seal of Quality

    Seals of Quality recognize the top 0.1% of laboratory products that consistently receive the highest customer review ratings and are designed to further assist scientists worldwide in making important purchasing decisions for their labs.

    The EnVision XCite provides exceptional sensitivity and speed with minimal downtime – backed by our global network of application scientists and engineers.

      Technologies included

      • Filter based fluorescence intensity (top and bottom)
      • Time-resolved fluorescence (top and bottom)
      • Luminescence, including glow, flash and dual luminescence
      • Filter-based absorbance
      • Fluorescence polarization

      Optional technologies

      • Standard Alpha technology
      • High-throughput Alpha technology
      • Monochromator-based fluorescence intensity
      • Monochromator-based absorbance detection
      • Laser-based time-resolved fluorescence
      • Ultra-sensitive luminescence

      ​​Key Features

      • Field upgradeable for changing application needs
      • User-changeable, label-specific optical mirror modules and filters for assay customization with positive identification of measurement configuration (barcodes)
      • Maximum flexibility with optional quad monochromator

      See full list of filters under the Resources.


      • 2 channel dispenser
      • Plate stacker (20 or 50 plates)
      • Temperature control up to 55ºC
      • Compatible with a wide range of automation systems
      • Signals VitroVivo for multimode detection (MMD) is tailored to the analysis of plate reader data and enables you to visualize, correlate, compare and analyze your data and share freely with your colleagues
      • Integrated barcode reading enables barcode reading from short right side and both long sides of the plate
      • Optional 21 CFR Part 11 support

      Outstanding Support

      We understand your science and applications - with our years of experience developing and supporting multimode plate readers and reagents. And with support from our global network of application scientists and engineers, you can be confident of minimal downtime.

      Part of a Total Solution for Screening

      EnVision is part of our complete solution for screening. For high-throughput screening, we offer assays and reagents, radioimmunoassays and radiometric detection, microplates and automation, in addition to multimode plate readers. We also offer solutions for phenotypic screening such as high-content screening systems and for data analysis such as Signals Image Artist

    • 21CFR Compatible
      Automation Compatible
      Detection Method
      Fluorescence Polarization
      Time-Resolved Fluorescence (TRF)
      Model Name
      EnVision XCite
      Quantity in a Package Amount
      1.0 each
      Unit Size
      1 Unit
    • The Spectra Viewer tool helps you visualize the spectral compatibility of fluorophores and fluorescent labelled probes so you can determine what filters are best for detection. Choose the appropriate Revvity multimode plate reader from the Select Machine drop-down menu. After selection, filters for the chosen instrument will be displayed automatically.

      • The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection. Omi, J., Watanabe-Takahashi, M., Igai, K. et al. Nat Commun 11, 162 (2020).
      • A nucleobase-binding pocket in a viral RNA-dependent RNA polymerase contributes to elongation complex stability. Wei Shi, Han-Qing Ye, Cheng-Lin Deng, Rui Li, Bo Zhang, Peng Gong. Nucleic Acids Research, Volume 48, Issue 3, 20 February 2020, Pages 1392–1405.
      • Structure of Mpro from COVID-19 virus and discovery of its inhibitors. Zhenming Jin, Xiaoyu Du, Yechun Xu, Yongqiang Deng et al. bioRxiv 2020.02.26.964882;
      • Anthralin Suppresses the Proliferation of Influenza Virus by Inhibiting the Cap-Binding and Endonuclease Activity of Viral RNA Polymerase. Hu Ao, Li Jing, Tang Wei, Liu Ge et al. Frontiers in Microbiology, Volume 11 (2020), Pages 178.
      • Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis. Zhihui Jia, Liming Yan, Zhilin Ren, Lijie Wu et al. Nucleic Acids Research, Volume 47, Issue 12, 09 July 2019, Pages 6538–6550,
      • Glycan-binding preferences and genetic evolution of human seasonal influenza A(H3N2) viruses during 1999-2007 in Taiwan. Wang Y-F, Chang C-F, Tsai H-P, Chi C-Y, Su I-J, Wang J-R. PLoS ONE (2018), 13(5): e0196727.
      • Antibody profiles to wheat germ cell-free system synthesized Plasmodium falciparum proteins correlate with protection from symptomatic malaria in Uganda. Kanoi, Bernard N et al. Vaccine (2017), 35(6): 873-881.
      • Novel Small Molecule Entry Inhibitors of Ebola Virus. Basu, Arnab et al. The Journal of Infectious Diseases (2016), 212 Suppl 2:S425-34.
      • A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein. Landeck, Natalie et al. Molecular Neurodegeneration (2016), 11(1):61.
      • Development of two novel high-throughput assays to quantify ubiquitylated proteins in cell lysates: application to screening of new anti-malarials. Mata-Cantero, Lydia et al. Malaria Journal (2015), 14:200.


    1-2 of 2 Resources
    Choosing the right plate reader

    For more than twenty years, our EnVision plate reader has been the proven leader in high throughput screening – and the EnVision®...

    Guidance for ensuring your EnVision multimode plate reader complies with 21 CFR Part 11

    Ensuring that laboratory processes are compliant with the regulations of the U.S. Food and Drug Administration (FDA), such as CFR...