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Citric Acid, [1,5-14C]-, EtOH Sol, 50 µCi (1.85 MBq)

Citric acid, labeled with C-14 at C1 and C5. 14C-citrate is commonly used to label long-chain fatty acids.

Feature Specification
Concentration 0.05 mCi/mL
Label Position Specifically Labeled

Citric acid, labeled with C-14 at C1 and C5. 14C-citrate is commonly used to label long-chain fatty acids.

Product variants
Unit Size: 50 µCi
Part #:
NEC160050UC
List price
USD 1,495.00
Your online price:
Unit Size: 250 µCi
Part #:
NEC160250UC
List price
USD 5,504.00
Your online price:
For research use only. Not for use in diagnostic procedures.

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Overview

ATP citrate lyase (ACL) is a cytosolic enzyme that catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a necessary cofactor. The ACL-dependent synthesis of acetyl-CoA is thought to be an essential step for the de novo synthesis of fatty acids and cholesterol. For this reason, inhibition of ACL has been pursued as a strategy to treat dyslipidemia and obesity.

Specifications

Concentration
0.05 mCi/mL
Molecular Weight
192.12
Specific Activity
100 - 124 mCi/mmol (3700 - 4588 MBq/mmol)
CAS Number
77-92-9
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer/Solvent
Ethanol : water (2:98)
Detection Modality
Radiometric
Label Position
Specifically Labeled
Molecular Formula
C6H8O7
Packaging
NENSure vial
Radioisotope
14C
Shipping Information
Blue Ice
Shipping Conditions
Shipped in Blue Ice
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
5°C
Unit Size
50 µCi

Resources

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Guide
Carbon-14 handling precautions

This document contains general information designed to provide a basic understanding of radiation safety for Carbon-14. While we...

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