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Citric Acid, [1,5-14C]-, EtOH Sol, 50 µCi (1.85 MBq)

Citric acid, labeled with C-14 at C1 and C5. 14C-citrate is commonly used to label long-chain fatty acids.

For research use only. Not for use in diagnostic procedures.

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Product Variants
Part number: NEC160050UC
Unit Size: 50 µCi
List price: USD 1,552.00
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USD 1,552.00
USD 1,552.00 /each
Part number: NEC160250UC
Unit Size: 250 µCi
List price: USD 5,715.00
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USD 0.00
USD 5,715.00 /each

Overview

ATP citrate lyase (ACL) is a cytosolic enzyme that catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a necessary cofactor. The ACL-dependent synthesis of acetyl-CoA is thought to be an essential step for the de novo synthesis of fatty acids and cholesterol. For this reason, inhibition of ACL has been pursued as a strategy to treat dyslipidemia and obesity.

Specifications

Concentration
0.05 mCi/mL
Molecular Weight
192.12
Application
Drug Discovery & Development
Brand
NEN Radiochemicals
Buffer
Ethanol : water (2:98)
Detection Method
Radiometric
Label Position
Specifically Labeled
Packaging
NENSure vial
Radioisotope
14C
Shipping Conditions
Shipped in Blue Ice
Special Ordering Information
This is a radioactive product - shipping address must have a license to receive radioactive materials.
Storage Conditions
5°C
Unit Size
50 µCi

Resources

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Guide
Carbon-14 handling precautions

This document contains general information designed to provide a basic understanding of radiation safety for Carbon-14. While we...

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NENSure: The safest packaging for radiochemicals

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