Citric acid, labeled with C-14 at C1 and C5. 14C-citrate is commonly used to label long-chain fatty acids.
For research use only. Not for use in diagnostic procedures.
ATP citrate lyase (ACL) is a cytosolic enzyme that catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a necessary cofactor. The ACL-dependent synthesis of acetyl-CoA is thought to be an essential step for the de novo synthesis of fatty acids and cholesterol. For this reason, inhibition of ACL has been pursued as a strategy to treat dyslipidemia and obesity.
Concentration |
0.05 mCi/mL
|
---|---|
Molecular Weight |
192.12
|
Application |
Drug Discovery & Development
|
---|---|
Brand |
NEN Radiochemicals
|
Buffer |
Ethanol : water (2:98)
|
Detection Method |
Radiometric
|
Label Position |
Specifically Labeled
|
Packaging |
NENSure vial
|
Radioisotope |
14C
|
Shipping Conditions |
Shipped in Blue Ice
|
Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
|
Storage Conditions |
5°C
|
Unit Size |
50 µCi
|
This document contains general information designed to provide a basic understanding of radiation safety for Carbon-14. While we...
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