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AlphaLISA SureFire Ultra Human Total WDR5 Detection Kit, 500 Assay Points

The AlphaLISA® SureFire® Ultra Human Total WDR5 assay is a sandwich immunoassay for quantitative detection of total WDR5 in cellular lysates using Alpha Technology.

Part Number: ALSU-TWDR-A500
Unit Size:
Part Number: ALSU-TWDR-A10K
Unit Size:
Part Number: ALSU-TWDR-A50K
Unit Size:
Part Number: ALSU-TWDR-A-HV
Unit Size:
  • WD repeat-containing protein 5 (WDR5) is a member of the WD40 repeat domain protein family. WDR5 is a core scaffolding component of histone methyltransferase complexes. New data demonstrates that the protein is involved in additional processes, ranging from expanded functions in the nucleus to controlling the integrity of cell division. The canonical function of WDR5 is as a core component of the SET1/MLL histone methyltransferase complexes. WDR5 has emerged as a prime target for anti-cancer drug discovery efforts including the PROTAC degrader approach.

    The AlphaLISA SureFire Human Total WDR5 Detection Kit is a sandwich immunoassay for the quantitative detection of total WDR5 in cellular lysates, using Alpha Technology.

    Formats:
    • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
    • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
    • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
    • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
    AlphaLISA SureFire Ultra kits are compatible with:
    • Cell and tissue lysates
    • Antibody modulators
    • Biotherapeutic antibodies
    Alpha SureFire kits can be used for:
    • Cellular kinase assays
    • Receptor activation studies
    • Screening

    For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

  • Application
    Protein Analysis & Detection
    Protein Detection
    Assay Target Class
    Phospho-protein
    Assay Technology
    Alpha
    Automation Compatible
    Yes
    Brand
    AlphaLISA SureFire Ultra
    Detection Method
    Alpha
    Experimental Type
    In vitro
    Target Species
    Human
    Therapeutic Area
    Oncology