The AlphaLISA™ SureFire® Ultra™ Mouse Phospho-TFEB (Ser211) assay is a sandwich immunoassay for quantitative detection of phospho-TFEB (Ser211) in cellular lysates using Alpha Technology.
For research use only. Not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Feature | Specification |
---|---|
Application | Cell Signaling |
Sample Volume | 10 µL |
The AlphaLISA™ SureFire® Ultra™ Mouse Phospho-TFEB (Ser211) assay is a sandwich immunoassay for quantitative detection of phospho-TFEB (Ser211) in cellular lysates using Alpha Technology.
For research use only. Not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Transcription factor EB (TFEB) plays a key role in the regulation of basic cellular processes, including lysosomal biogenesis and autophagy. While phosphorylated TFEB is found in the cytoplasm, dephosphorylated TFEB moves to the nucleus to initiate the transcription of target genes. The subcellular location and function of TFEB are regulated by phosphorylation at the lysosomal surface, which is controlled by mechanistic target of rapamycin (mTOR). TFEB is implicated in various diseases, such as lysosomal storage disorders, neurodegenerative diseases, cancers, and metabolic disorders.
The AlphaLISA SureFire Ultra Mouse Phospho-TFEB (Ser211) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-TFEB (Ser211) in cellular lysates, using Alpha Technology.
Application |
Cell Signaling
|
---|---|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Modality |
Alpha
|
Lysis Buffer Compatibility |
Lysis Buffer
|
Molecular Modification |
Phosphorylation
|
Product Group |
Kit
|
Sample Volume |
10 µL
|
Shipping Conditions |
Shipped in Blue Ice
|
Target |
TFEB
|
Target Class |
Phosphoproteins
|
Target Species |
Mouse
|
Technology |
Alpha
|
Therapeutic Area |
Neuroscience
Oncology
|
Unit Size |
500 Assay Points
|
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