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AlphaLISA Surefire Ultra Total TDP-43 Detection Kit, 500 Assay Points

The AlphaLISA® SureFire® Ultra Human Total TDP-43 assay is a sandwich immunoassay for quantitative detection of total TDP-43 in cellular lysates using Alpha Technology.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Product Variants
Part number: ALSU-TTDP43-A500
Unit Size: 500 Assay Points
List price: USD 2,486.00
Your price:
USD 2,486.00
USD 2,486.00 /each
Part number: ALSU-TTDP43-A10K
Unit Size: 10,000 Assay Points
List price: USD 15,110.00
Your price:
USD 0.00
USD 15,110.00 /each
Part number: ALSU-TTDP43-A50K
Unit Size: 50,000 Assay Points
List price: USD 48,780.00
Your price:
USD 0.00
USD 48,780.00 /each
Part number: ALSU-TTDP43-A-HV
Unit Size: 100 Assay Points
List price: USD 740.59
Your price:
USD 0.00
USD 740.59 /each

Overview

TAR DNA binding protein 43 (TDP-43) is a nucleic acid binding protein involved in RNA-related metabolism. In pathological conditions (mutation or deregulation), TDP-43 forms insoluble inclusion bodies in the cytoplasm of neurons in the brain and spinal cord. Aggregated TDP-43 has been identified as a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar dementia (FTLD), and more widely in several neurodegenerative diseases such as Alzheimer’s disease.

The AlphaLISA SureFire Ultra Human Total TDP-43 Detection Kit is a sandwich immunoassay for the quantitative detection of total TDP-43 in cellular lysates, using Alpha Technology.

Formats:
  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
AlphaLISA SureFire Ultra kits are compatible with:
  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies
Alpha SureFire kits can be used for:
  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Application
Protein Detection
Assay Points
500
Assay Technology
Alpha
Automation Compatible
Yes
Brand
AlphaLISA SureFire Ultra
Detection Method
Alpha
Experimental Type
In vitro
Shipping Conditions
Shipped in Blue Ice
Target Species
Human
Therapeutic Area
Neuroscience
Unit Size
500 Assay Points

Video gallery

Resources

1-4 of 4 Resources
Guide
AlphaLISA SureFire Ultra assay optimization

This guide outlines further possible optimization of cellular and immunoassay parameters to ensure the best possible results are...

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Brochure
Alpha SureFire Ultra no-wash immunoassay catalog

Discover Alpha SureFire® Ultra™ assays, the no-wash cellular kinase assays leveraging Revvity's exclusive bead-based technology...

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Application Note
Characterizing Chemokine Receptor Inhibitors with AlphaLISA SureFire Ultra

Therapeutic antibodies directed to cell surface receptors are increasingly being developed as treatments for a variety of diseases...

Guide
Download your guide about neurodegenerative diseases

<p>Emerging pathways to neuroinflammation and neurodegeneration</p><p>Neurodegenerative diseases, such as amyotrophic lateral sclerosis...</p>

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SDS, COAs, Manuals and more

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