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AlphaLISA SureFire Ultra Human Total Parkin Detection Kit, 10,000 Assay Points

The AlphaLISA® SureFire® Ultra Human Total Parkin assay is a sandwich immunoassay for quantitative detection of total Parkin in cellular lysates using Alpha Technology.

Part Number: ALSU-TPARK-A10K
Unit Size: 10,000 Assay Points
Part Number: ALSU-TPARK-A50K
Unit Size: 50,000 Assay Points
Part Number: ALSU-TPARK-A500
Unit Size: 500 Assay Points
Part Number: ALSU-TPARK-A-HV
Unit Size: 100 Assay Points
  • Parkin, encoded by the PARK2 gene, is an E3 ubiquitin ligase which has a neuroprotective role in combination with the Ser/Thr kinase PINK1 by acting in a mitochondrial quality control pathway. Since mitochondria are continuously exposed to intra and extra mitochondrial threats including reactive oxygen species (ROS), the removal of damaged mitochondria is critical for maintaining cellular homeostasis. Dysfunction of Parkin represents both a predominant cause of familial parkinsonism but also a formal risk factor for the more common, sporadic form of Parkinson's disease (PD).

    The AlphaLISA SureFire Human Total Parkin Detection Kit is a sandwich immunoassay for the quantitative detection of total Parkin in cellular lysates, using Alpha Technology.

    Formats:
    • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
    • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
    • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
    • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
    AlphaLISA SureFire Ultra kits are compatible with:
    • Cell and tissue lysates
    • Antibody modulators
    • Biotherapeutic antibodies
    Alpha SureFire kits can be used for:
    • Cellular kinase assays
    • Receptor activation studies
    • Screening

    For research use only; not for diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

  • Automation Compatible
    Yes
    Application
    Protein Detection
    Assay Target
    Parkin
    Assay Technology
    Alpha
    Detection Method
    Alpha
    Experimental Type
    In vitro
    Target Species
    Human
    Therapeutic Area
    Neuroscience
    Brand
    AlphaLISA SureFire Ultra
    Unit Size
    10,000 Assay Points