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AlphaLISA Surefire Ultra Total NRF2 Detection Kit, 500 Assay Points

The AlphaLISA® SureFire® Ultra Human Total Nrf2 assay is a sandwich immunoassay for quantitative detection of total Nrf2 in cellular lysates using Alpha Technology.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Product Variants
Part number: ALSU-TNRF2-A500
Unit Size: 500 Assay Points
List price: USD 2,346.00
Your price:
USD 2,346.00
USD 2,346.00 /each
Part number: ALSU-TNRF2-A10K
Unit Size: 10,000 Assay Points
List price: USD 14,270.00
Your price:
USD 0.00
USD 14,270.00 /each
Part number: ALSU-TNRF2-A50K
Unit Size: 50,000 Assay Points
List price: USD 46,060.00
Your price:
USD 0.00
USD 46,060.00 /each
Part number: ALSU-TNRF2-A-HV
Unit Size: 100 Assay Points
List price: USD 694.44
Your price:
USD 0.00
USD 694.44 /each

Overview

Nuclear factor erythroid 2-related factor 2 (Nrf2), also known as nuclear factor erythroid-derived 2-like 2, is a basic leucine zipper (bZIP) encoded by the NFE2L2 gene. Based on preliminary research, Nrf2 may regulate the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation. NRF2 is thought to play a pleiotropic function in the control of metabolism, inflammation, autophagy, proteostasis, mitochondrial physiology, and immunological responses. For the treatment of illnesses brought on by oxidative stress, numerous medications that promote the NRF2 pathway are being investigated.

The AlphaLISA SureFire Human Total Nrf2 Detection Kit is a sandwich immunoassay for the quantitative detection of total Nrf2 in cellular lysates, using Alpha Technology.

Formats
  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
AlphaLISA SureFire Ultra kits are compatible with
  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies
Alpha SureFire kits can be used for
  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Application
Protein Detection
Assay Technology
Alpha
Automation Compatible
Yes
Brand
AlphaLISA SureFire Ultra
Detection Method
Alpha
Experimental Type
In vitro
Shipping Conditions
Shipped in Blue Ice
Target Species
Human
Therapeutic Area
Autoimmunity
Immuno-oncology
Inflammation
Unit Size
500 Assay Points

Video gallery

Resources

1-2 of 2 Resources
Guide
AlphaLISA SureFire Ultra assay optimization

This guide outlines further possible optimization of cellular and immunoassay parameters to ensure the best possible results are...

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Alpha SureFire Ultra no-wash immunoassay catalog

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