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The AlphaLISA® SureFire® Ultra™ Human Total NPM assay is a sandwich immunoassay for quantitative detection of total NPM in cellular lysates using Alpha Technology.
Nucleophosmin (NPM, Nucleolar Phosphoprotein B23, No38, or Numatrin) is a highly conserved, abundant nucleolar protein found in the nuclei of proliferating cells. NPM is a chaperone protein that shuttles rapidly between the nucleus and cytoplasm. It plays key roles in ribosome biogenesis, centrosome duplication, genomic stability, cell cycle progression, and apoptosis. NPM overexpression, mutation, rearrangement, or deletion, is associated with several types of cancer.
The AlphaLISA SureFire Human Total NPM Detection Kit Detection Kit is a sandwich immunoassay for the quantitative detection of total NPM in cellular lysates, using Alpha Technology.
Protein Analysis & Detection
|Assay Target Class
AlphaLISA SureFire Ultra