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AlphaLISA SureFire Ultra Human Phospho-IRF5 (Ser446) Detection Kit, 500 Assay Points

The AlphaLISA™ SureFire®  Ultra™ Human Phospho-IRF5 (Ser446) assay is a sandwich immunoassay for quantitative detection of phospho-IRF5 (Ser446) in cellular lysates using Alpha Technology.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).

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Product Variants
Part number: ALSU-PIRF5-A-HV
Unit Size: 100 Assay Points
List price: USD 694.00
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USD 0.00
USD 694.00 /each
Part number: ALSU-PIRF5-A500
Unit Size: 500 Assay Points
List price: USD 2,346.00
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USD 2,346.00
USD 2,346.00 /each
Part number: ALSU-PIRF5-A10K
Unit Size: 10,000 Assay Points
List price: USD 14,270.00
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USD 0.00
USD 14,270.00 /each
Part number: ALSU-PIRF5-A50K
Unit Size: 50,000 Assay Points
List price: USD 46,060.00
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USD 0.00
USD 46,060.00 /each

Overview

Interferon regulator factor 5, IRF5, is a transcriptional regulator of type I interferon (IFN-alpha and IFN-beta)-dependent immune responses. This transcription factor plays a key role in the innate immune response against DNA and RNA viruses. IRF5 is present in the cytoplasm of uninfected cells in an inactive form. Various mediators of the pathways that follow viral infection can overexpress and phosphorylate IRF5. IRF5 is associated with various cancers and autoimmune diseases.

 

The AlphaLISA SureFire Ultra Human Phospho-IRF5 (Ser446) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-IRF5 (Ser446) in cellular lysates, using Alpha Technology.

 Formats:

  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with:

  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies

Alpha SureFire kits can be used for:

  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Application
Cell Signaling
Automation Compatible
Yes
Brand
AlphaLISA SureFire Ultra
Detection Modality
Alpha
Molecular Modification
Phosphorylation
Predicted Species Reactivity
Human
Product Group
Kit
Sample Volume
10 µL
Shipping Conditions
Shipped in Blue Ice
Target
IRF5
Target Class
Phosphoproteins
Technology
Alpha
Therapeutic Area
Inflammation
Oncology
Unit Size
500 Assay Points

Resources

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Alpha SureFire Ultra no-wash immunoassay catalog

Discover Alpha SureFire® Ultra™ assays, the no-wash cellular kinase assays leveraging Revvity's exclusive bead-based technology...

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