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AlphaLISA Surefire Ultra Total IKKB Detection Kit, 500 Assay Points

The AlphaLISA® SureFire® Ultra Human Total IKKβ assay is a sandwich immunoassay for quantitative detection of total IKKβ in cellular lysates using Alpha Technology.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

Product Variants
Part number: ALSU-TIKKB-A500
Unit Size: 500 Assay Points
List price: USD 2,486.00
Your price:
USD 2,486.00
USD 2,486.00 /each
Part number: ALSU-TIKKB-A10K
Unit Size: 10,000 Assay Points
List price: USD 15,110.00
Your price:
USD 0.00
USD 15,110.00 /each
Part number: ALSU-TIKKB-A50K
Unit Size: 50,000 Assay Points
List price: USD 48,780.00
Your price:
USD 0.00
USD 48,780.00 /each
Part number: ALSU-TIKKB-A-HV
Unit Size: 100 Assay Points
List price: USD 740.59
Your price:
USD 0.00
USD 740.59 /each

Overview

Inhibitor of nuclear factor kappa-B kinase subunit β (IKKβ) is a protein subunit of IkB kinase, which is an enzyme complex involved in propagating cellular response to inflammation. Activated IKKβ phosphorylates IkBα, preventing IkBα from inhibiting NF-kB which then frees NF-kB and allows it to enter the nucleus of the cell, where it activates various genes involved in inflammation and other immune responses. The IKKβ signaling pathway is associated with numerous therapeutic areas, including diseases such as multiple sclerosis, rheumatoid arthritis, psoriasis, and many types of cancers.

The AlphaLISA SureFire Ultra Human Total IKKβ Detection Kit is a sandwich immunoassay for the quantitative detection of total IKKβ in cellular lysates, using Alpha Technology.

Formats:
  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.
AlphaLISA SureFire Ultra kits are compatible with:
  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies
Alpha SureFire kits can be used for:
  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Application
Protein Analysis & Detection
Protein Detection
Assay Points
500
Assay Target Class
Phospho-protein
Assay Technology
Alpha
Automation Compatible
Yes
Brand
AlphaLISA SureFire Ultra
Detection Method
Alpha
Experimental Type
In vitro
Target Species
Human
Therapeutic Area
Autoimmunity
Immuno-oncology
Oncology
Unit Size
500 Assay Points

Video gallery

Resources

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SDS, COAs, Manuals and more

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