The AlphaLISA™ SureFire® Ultra™ Human and Mouse Phospho-FAK (Tyr576/577) assay is a sandwich immunoassay for quantitative detection of phospho-FAK (Tyr576/577) in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption and disposal requirements under European REACH regulations (EC 1907/2006).
Feature | Specification |
---|---|
Application | Cell Signaling |
Sample Volume | 10 µL |
The AlphaLISA™ SureFire® Ultra™ Human and Mouse Phospho-FAK (Tyr576/577) assay is a sandwich immunoassay for quantitative detection of phospho-FAK (Tyr576/577) in cellular lysates using Alpha Technology.
Focal adhesion kinase (FAK), also known as protein tyrosine kinase 2 (PTK2), is a non-receptor tyrosine kinase that can be activated by growth factor receptors, cytokine receptors, and GPCRs. FAK is a central regulator of ECM/integrin and cadherin signaling and plays a role in cell adhesion, cell junction, migration, survival, and mechanosensing. Increased FAK expression and phosphorylation is implicated in increased tumor cell adhesion, tumor cell motility and invasion, and with fibroblast migration on fibronectin in tissue fibrosis.
The AlphaLISA SureFire Human and Mouse Phospho-FAK (Tyr576/577) Detection Kit is a sandwich immunoassay for the quantitative detection of phospho-FAK (Tyr576/577) in cellular lysates, using Alpha Technology.
Application |
Cell Signaling
|
---|---|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Modality |
Alpha
|
Molecular Modification |
Phosphorylation
|
Product Group |
Kit
|
Sample Volume |
10 µL
|
Shipping Conditions |
Shipped in Blue Ice
|
Target |
FAK
|
Target Class |
Phosphoproteins
|
Target Species |
Human
Mouse
|
Technology |
Alpha
|
Therapeutic Area |
Oncology
|
Unit Size |
500 Assay Points
|
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