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AlphaLISA SureFire Ultra Human Total Cyclin D2 Detection Kit, 100 Assay Points

The AlphaLISA™ SureFire®  Ultra™ Human Total Cyclin D2 assay is a sandwich immunoassay for quantitative detection of total Cyclin D2 in cellular lysates using Alpha Technology.

For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).

Product Variants
Part number: ALSU-TCYCD2-A-HV
Unit Size: 100 Assay Points
List price: USD 694.00
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USD 694.00
USD 694.00 /each
Part number: ALSU-TCYCD2-A500
Unit Size: 500 Assay Points
List price: USD 2,346.00
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USD 0.00
USD 2,346.00 /each
Part number: ALSU-TCYCD2-A10K
Unit Size: 10,000 Assay Points
List price: USD 14,270.00
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USD 0.00
USD 14,270.00 /each
Part number: ALSU-TCYCD2-A50K
Unit Size: 50,000 Assay Points
List price: USD 46,060.00
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USD 0.00
USD 46,060.00 /each

Overview

Cyclin D2 (CCND2) plays an important role in cell cycle regulation, differentiation, and malignant transformation. Overall, D-type cyclins (D1, D2, and D3) are involved in the regulation of transition from G1 to S during the cell cycle. Cyclin D activity is regulated through its mitogen-activated transcription, binding to CDK4/6, phosphorylation, ubiquitylation, nuclear export, and degradation. Accumulation of Cyclin D2 is the most common disease mechanism associated with CCND2-associated disorders.

 

The AlphaLISA SureFire Ultra Human Total Cyclin D2 Detection Kit is a sandwich immunoassay for the quantitative detection of total Cyclin D2 in cellular lysates, using Alpha Technology.

 Formats:

  • The HV (high volume) kit contains reagents to run 100 wells in 96-well format, using a 60 μL reaction volume.
  • The 500-point kit contains enough reagents to run 500 wells in 384-well format, using a 20 μL reaction volume.
  • The 10,000-point kit contains enough reagents to run 10,000 wells in 384-well format, using a 20 μL reaction volume.
  • The 50,000-point kit contains enough reagents to run 50,000 wells in 384-well format, using a 20 μL reaction volume.

AlphaLISA SureFire Ultra kits are compatible with:

  • Cell and tissue lysates
  • Antibody modulators
  • Biotherapeutic antibodies

Alpha SureFire kits can be used for:

  • Cellular kinase assays
  • Receptor activation studies
  • Screening

Specifications

Assay Target
Cyclin D2
Automation Compatible
Yes
Brand
AlphaLISA SureFire Ultra
Detection Method
Alpha
Predicted Species Reactivity
Human
Shipping Conditions
Shipped in Blue Ice
Therapeutic Area
Oncology
Unit Size
100 Assay Points

Resources

1-2 of 2 Resources
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Guide
AlphaLISA SureFire Ultra: the ultimate guide for successful experiments

The definitive guide for setting up a successful AlphaLISA SureFire Ultra assay

Several biological processes are regulated by...

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Brochure
Alpha SureFire Ultra no-wash immunoassay catalog

Discover Alpha SureFire® Ultra™ assays, the no-wash cellular kinase assays leveraging Revvity's exclusive bead-based technology...

SDS, COAs, Manuals and more

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