The AlphaLISA™ SureFire® Ultra™ Human Total Cyclin D2 assay is a sandwich immunoassay for quantitative detection of total Cyclin D2 in cellular lysates using Alpha Technology.
For research use only. Not for use in diagnostic procedures. All products to be used in accordance with applicable laws and regulations including without limitation, consumption & disposal requirements under European REACH regulations (EC 1907/2006).
Cyclin D2 (CCND2) plays an important role in cell cycle regulation, differentiation, and malignant transformation. Overall, D-type cyclins (D1, D2, and D3) are involved in the regulation of transition from G1 to S during the cell cycle. Cyclin D activity is regulated through its mitogen-activated transcription, binding to CDK4/6, phosphorylation, ubiquitylation, nuclear export, and degradation. Accumulation of Cyclin D2 is the most common disease mechanism associated with CCND2-associated disorders.
The AlphaLISA SureFire Ultra Human Total Cyclin D2 Detection Kit is a sandwich immunoassay for the quantitative detection of total Cyclin D2 in cellular lysates, using Alpha Technology.
Formats:
AlphaLISA SureFire Ultra kits are compatible with:
Alpha SureFire kits can be used for:
Assay Target |
Cyclin D2
|
---|---|
Automation Compatible |
Yes
|
Brand |
AlphaLISA SureFire Ultra
|
Detection Method |
Alpha
|
Predicted Species Reactivity |
Human
|
Shipping Conditions |
Shipped in Blue Ice
|
Therapeutic Area |
Oncology
|
Unit Size |
100 Assay Points
|
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